Evidence map›Paper›PMID 41087445›Full record

ArticleScientific reports2025

Determinants of diabetic ketoacidosis among adults with diabetes mellitus at the Ambo town Hospitals, Ethiopia.

Lalisa Masarat, Habtamu Oljirah, Wubet Tazeb Wondie, Selemon Gebrezgabiher Asgedom, Fentaw Wassie Feleke, Getachew Sale Mezgebu, Habtamu Temesgen, Wubetu Woyraw, Wabi Temesgen Atinafu, Derese Bekele Daba and 3 more

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Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

13 authors.

Lalisa MasaratDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Habtamu OljirahDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Wubet Tazeb WondieDepartment of Pediatrics and Child Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Selemon Gebrezgabiher AsgedomSchool of Medicine, Yekatit 12 Hospital Medical College, Addis Ababa Health Office, Federal Ministry of Health, Addis Ababa, Ethiopia.
Fentaw Wassie FelekeDepartment of Public Health, College of Health Science, Woldia University, Woldia, Ethiopia.
Getachew Sale MezgebuDepartment of Human Nutrition, School of Nutrition, Food Science and Technology, Hawassa University, Hawassa, Ethiopia.
Habtamu TemesgenDepartment of Human Nutrition, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia.
Wubetu WoyrawDepartment of Human Nutrition, College of Medicine and Health Science, Debre Markos University, Debre Markos, Ethiopia.
Wabi Temesgen AtinafuDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Derese Bekele DabaDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Milion Gebrewold AbdiALERT Comprehensive Specialized Hospital, Federal Ministry of Health, Addis Ababa, Ethiopia.
Wakuma Amsalu GemedeDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Kefyalew Taye BeleteDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia. kefyalewtaye24@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic ketoacidosis (DKA) is a life-threatening hyperglycemic emergency with high morbidity and mortality in diabetes. This study explored determinants of diabetic ketoacidosis among adult diabetic patients in Ambo Town, Ethiopia. An unmatched case-control study was conducted from February 1 to March 30, 2024, involving 78 DKA cases and 230 controls (patients with diabetes mellitus and without DKA). Data were collected through structured questionnaires and chart reviews. Quality assurance measures included pretesting, data collector training, and supervision. Data were analyzed using SPSS version 25, with binary logistic regression identifying significant determinants, considering p < 0.05 as significant. The mean age of participants was 45.87 years (± 17.12 SD). Statistically significant determinants of DKA included being a type 1 diabetic [AOR 3.5; 95% CI 1.54-7.96], presence of comorbidities [AOR 4.82; 95% CI 2.03-11.42], irregular attendance at diabetic clinic appointments [AOR 6.14; 95% CI 2.25-14.7], discontinuation of prescribed medications [AOR 3.07; 95% CI 1.34-7.04], lack of health insurance [AOR 5.00; 95% CI 2.22-11.26] and other diabetes-related complications [AOR 4.25; 95% CI 1.59-11.3]. Therefore, Interventions should target follow-up care, medication adherence, insurance access, and comorbidity management to reduce risk and improve outcomes.

Indexed as

Diabetes MellitusDiabetes Mellitus, Type 1Diabetic KetoacidosisAdultAgedCase-Control StudiesComorbidityEthiopiaFemaleHospitalsHumansMaleMiddle AgedRisk FactorsDeterminantsDiabetes mellitusDiabetic ketoacidosisEthiopia

Identifiers

PMID41087445
PMCPMC12521567

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