ArticleBMC gastroenterology2025
Association of cardiometabolic index with non-alcoholic fatty liver disease among Iranian adults of the amol cohort study.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundSeveral studies have demonstrated that the cardiometabolic index (CMI) is associated with multiple health conditions. These include kidney diseases, cardiovascular diseases, stroke, and hypertension. The objective of the present research was to investigate the relationship of CMI with the risk of non-alcoholic fatty liver disease (NAFLD) in a sample of the Iranian population.
methodsThis cross-sectional study included 3,120 participants from the second phase of the Amol cohort study. Ultrasound scanning was utilized to diagnose the NAFLD. The hepatic steatosis index (HSI), fatty liver index (FLI), and CMI values were calculated using standard equations. Multivariate and univariate logistic regression models were employed to investigate the relationship between CMI and NAFLD, FLI, and HSI.
resultsIn the adjusted model, we found that the likelihood of NAFLD increased in the second and last tertiles of CMI compared to the first tertile (T). For NAFLD the odds ratio (OR) were 1.883 (95% confidence interval (CI): 1.487-3.653) in T
conclusionsThe current study showed a significant association between CMI and NAFLD, as measured by ultrasound, FLI, and HSI. However, due to the cross-sectional design, causal inference is limited, and further prospective studies are needed to validate these results.
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