ReviewCureus2025
Near-Infrared Fluorescence Imaging in General Surgery: Applications in Vascularization, Tumor Margin Detection, and Biliary Anatomy.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Global evolution of robot-assisted cholecystectomy research in the era of artificial intelligence: a bibliometric and knowledge-mapping study.Journal of robotic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Near-infrared fluorescence (NIRF) imaging has emerged as a transformative intraoperative tool in general surgery, helping in vascular surgery interventions, tumor margin detection in different specialties, and biliary anatomy with high sensitivity and safety. Indocyanine green remains the gold-standard fluorescent agent, widely applied in angiography, tumor margin detection, and fluorescence cholangiography, consistently improving surgical safety and efficiency with exceedingly low complication rates. Recent advances and trends include activatable and targeted probes, near-infrared II fluorophores, and nanoparticle-based agents, which expand specificity, depth of imaging, and multiplexing capacity. Integration with robotic systems in general surgery practice and artificial intelligence may further strengthen the precision of fluorescence-guided surgery, providing automated interpretation and workflow integration. Clinical outcomes demonstrate reduced operative times, improved anatomical visualization during operations, and enhanced tumor resection accuracy, while emerging technologies promise broader applications in complex oncologic and hepatopancreatobiliary surgery. Taken together, NIRF imaging represents a rapidly evolving field with the potential to redefine intraoperative guidance and precision in general surgery.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.