ReviewMedical journal of the Islamic Republic of Iran2025
Prevalence of Acne Vulgaris Among Women with Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.
Review in Medical journal of the Islamic Republic of Iran, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Acne vulgaris is one of the most common dermatological conditions worldwide, particularly affecting women of reproductive age. It is often linked to underlying hormonal imbalances, including those seen in polycystic ovary syndrome (PCOS). PCOS is a prevalent endocrine disorder characterized by hyperandrogenism and insulin resistance, both of which contribute to acne vulgaris development. This systematic review and meta-analysis aimed to estimate the global prevalence of acne vulgaris among women with PCOS and identify contributing factors, thereby highlighting the burden of this skin condition in the context of a common endocrine disorder. Methods: In accordance with the PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) and Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines, a systematic review of cross-sectional studies was conducted to assess the prevalence of acne vulgaris among women with PCOS. The literature search included studies published up to January 2025 and was performed in 5 major databases: PubMed, EMBASE, Scopus, Web of Science, and Google Scholar. Study selection was guided by the POLIS framework, focusing on women diagnosed with PCOS based on established criteria (Rotterdam, National Institute of Health [NIH], or Androgen Excess Society [AES]). Only cross-sectional studies reporting the prevalence of acne vulgaris in this population were included. A random-effects (REM) meta-analysis was performed using data from 95 eligible studies. Subgroup analyses were conducted based on geographical region, age, body mass index (BMI), PCOS diagnostic criteria, and acne vulgaris severity to explore sources of heterogeneity. Results: As per the findings, acne vulgaris, the pooled prevalence of which was 49% (95% CI: 47%-52%), determined 95 studies, with high heterogeneity (I² = 98.86%, Conclusion: The prevalence of acne vulgaris among women with PCOS varies widely across studies, with subgroup analyses revealing a range influenced by factors such as region, age group, and diagnostic criteria. These findings highlight the need for standardized diagnostic tools for PCOS and comprehensive management approaches that address hormonal, metabolic, and psychological aspects to improve outcomes for affected women.
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