Evidence map›Paper›PMID 41091165›Full record

ArticleHuman genetics2025

Differentiating the demographic histories and local adaptations of middle-altitude Qiang and Tibetan people.

Qiuxia Sun, Yuhang Feng, Zhiyong Wang, Yuntao Sun, Lintao Luo, Jing Cheng, Fengxiao Bu, Yu Lu, Yan Liu, Chao Liu and 4 more

Abstract read
PubMed Publisher
In one paragraph

Article in Human genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Qiuxia SunDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Yuhang FengDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Zhiyong WangDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Yuntao SunDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Lintao LuoDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Jing ChengDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Fengxiao BuDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Yu LuDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Yan LiuDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China.
Chao LiuAnti-Drug Technology Center of Guangdong Province, Guangdong, 510000, China.
Huijun YuanDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China. yuanhj301@163.com.
Renkuan TangDepartment of Forensic Medicine, College of Basic Medicine, Chongqing Medical University, Chongqing, 400331, China. renktang2012@163.com.
Mengge WangDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China. Menggewang2021@163.com.
Guanglin HeDepartment of Oto-Rhino-Laryngology and Institute of Rare Diseases, Frontiers Science Center for Disease-related Molecular Network, West China Hospital of Sichuan University, Sichuan University, Chengdu, 610000, China. guanglinhescu@163.com.

Funding

Chongqing Natural Science Foundation Innovation and Development Joint Fund CSTB2024NSCQ-LZX0005National Natural Science Foundation of China 82202078National Natural Science Foundation of China 82402203the Center for Archaeological Science of Sichuan University 23SASA01
6 · The paper itself

Abstract

Genomic resources from Tibeto-Burman (TB)-speaking populations are underrepresented in human genome research, limiting the understanding of their evolutionary history and health-related genetic influences. We genotyped 95 individuals, including Baima and Amdo Tibetans from Jiuzhaigou on the eastern Qinghai-Xizang Plateau and Qiang from Mianyang Prefecture in Sichuan Province. These data were jointly analyzed with 1722 genomes from modern and ancient East Asian populations. Clustering patterns revealed by principal component analysis suggested that the Tibetan and Qiang populations formed three distinct genetic clines, which were supported by model-based ADMIXTURE and fineSTRUCTURE analyses, highlighting complex population histories and unique genetic clusters among the Qiang and Tibetan people. Shared genetic drift estimated via f

Indexed as

Adaptation, PhysiologicalAltitudeEast Asian PeopleEthnicityGenetics, PopulationChinaGene FlowGenetic DriftGenome, HumanGenotypeHumansPrincipal Component AnalysisTibet

Identifiers

PMID41091165

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.