Evidence map›Paper›PMID 41094882›Full record

ArticleSensors (Basel, Switzerland)2025

Monitoring Single DNA Docking Site Activity with Sequential Modes of an Optoplasmonic Whispering-Gallery Mode Biosensor.

Narima Eerqing, Ekaterina Zossimova, Sivaraman Subramanian, Hsin-Yu Wu, Frank Vollmer

Abstract read
In one paragraph

Article in Sensors (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Narima EerqingLiving Systems Institute, University of Exeter, Exeter EX4 4QD, UK.ORCID 0000-0001-6238-7528
Ekaterina ZossimovaLiving Systems Institute, University of Exeter, Exeter EX4 4QD, UK.ORCID 0000-0002-5286-6194
Sivaraman SubramanianLiving Systems Institute, University of Exeter, Exeter EX4 4QD, UK.
Hsin-Yu WuLiving Systems Institute, University of Exeter, Exeter EX4 4QD, UK.
Frank VollmerLiving Systems Institute, University of Exeter, Exeter EX4 4QD, UK.

Funding

Engineering and Physical Sciences Research Council EP/R031428/1
6 · The paper itself

Abstract

In recent years, there has been rapid advancement in single-molecule techniques, driven by their unparalleled precision in studying molecules whose sizes are beyond the diffraction limit. Among these techniques, optoplasmonic whispering gallery mode sensing has demonstrated great potential in label-free single-molecule characterization. It combines the principles of localized surface plasmon resonance (LSPR) and whispering gallery mode (WGM) sensing, offering exceptional sensing capabilities, even at the level of single ions. However, current optoplasmonic WGM sensing operates in a multiplexed channel, making it challenging to focus on individual binding sites of analyte molecules. In this article, we characterize different binding sites of DNA analyte molecules hybridizing to docking strands on the optoplasmonic WGM sensor, using the ratio of the resonance shift between sequential polar WGM modes. We identify specific docking sites that undergo transient interactions and eventually hybridize with the complementary analyte strands permanently.

Indexed as

Biosensing TechniquesDNABinding SitesSurface Plasmon ResonanceDNAmultiplexed sensingoptoplasmonicplasmonicssingle-moleculewhispering-gallery modes

Identifiers

PMID41094882
PMCPMC12527096

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.