Evidence mapPaperPMID 41096941Full record

ArticleInternational journal of molecular sciences2025

Short-Term: Cellular Metabolism and Gene Expression During the Onset of Diabetic Kidney Disease: A Diabetes Mellitus Experimental Model.

Jéssica Encinas, Glaucia Veiga, Joyce Raimundo, Matheus Perez, Giuliana Petri, Renan Cavalheiro, Pedro Reis, Laura Maifrino, Beatriz Alves, Fernando Fonseca

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jéssica EncinasLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.ORCID 0000-0001-6514-314X
Glaucia VeigaLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.ORCID 0000-0002-6097-2341
Joyce RaimundoLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.
Matheus PerezLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.
Giuliana PetriCoordenação da Comissão de Ética no uso de Animais, Centro Universitário FMABC, Santo André 09060-870, Brazil.
Renan CavalheiroDepartamento de Morfologia e Fisiologia, Centro Universitário FMABC, Santo André 09060-870, Brazil.
Pedro ReisLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.ORCID 0000-0002-1248-815X
Laura MaifrinoLaboratório de Estudos Morfoquantitativo e Imunohistoquímica (LEMI), Departamento Morfologia, Universidade São Judas Tadeu, São Paulo 03166-000, Brazil.ORCID 0000-0002-9456-192X
Beatriz AlvesLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.
Fernando FonsecaLaboratório de Análises Clínicas, Centro Universitário FMABC, Santo André 09060-870, Brazil.ORCID 0000-0003-1223-1589

Funding

Coordenação de Aperfeiçoamento de Pessoal de Nível Superior 1785559Fundação de Amparo à Pesquisa do Estado de São Paulo 2018/24808-0
6 · The paper itself

Abstract

Diabetes is a chronic disease with a rising global prevalence. Research focuses on understanding its metabolic implications and early signaling of disease onset and complications, particularly the interconnected effects on the kidneys and brain. The objective of this study was to evaluate the expression profile in the genes

Indexed as

Diabetes Mellitus, ExperimentalDiabetic NephropathiesAnimalsBrainCollagenDisease Models, AnimalGene Expression RegulationHypoxia-Inducible Factor 1, alpha SubunitKidneyMaleRatsRats, WistarVascular Endothelial Growth Factor ACollagenHif1a protein, ratHypoxia-Inducible Factor 1, alpha SubunitVascular Endothelial Growth Factor Avascular endothelial growth factor A, ratbiomarkerscollagen depositiondiabetes complications

Identifiers

PMID41096941
PMCPMC12524569

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.