Evidence map›Paper›PMID 41097034›Full record

ArticleInternational journal of molecular sciences2025

Custom Gene Panel Analysis Identifies Novel Polymorphisms Associated with Clopidogrel Response in Patients Undergoing Percutaneous Coronary Intervention with Stent.

Alba Antúnez-Rodríguez, Sonia García-Rodríguez, Ana Pozo-Agundo, Jesús Gabriel Sánchez-Ramos, Eduardo Moreno-Escobar, José Matías Triviño-Juárez, María Jesús Álvarez-Cubero, Luis Javier Martínez-González, Cristina Lucía Dávila-Fajardo

Abstract read
In one paragraph

Article in International journal of molecular sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alba Antúnez-RodríguezCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-3963-6546
Sonia García-RodríguezCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0001-8959-4797
Ana Pozo-AgundoCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0003-2188-6296
Jesús Gabriel Sánchez-RamosCardiology Department, Hospital Universitario Clínico San Cecilio, Avenida de la Innovación s/n, 18016 Granada, Spain.ORCID 0000-0001-5607-0284
Eduardo Moreno-EscobarCardiology Department, Hospital Universitario Clínico San Cecilio, Avenida de la Innovación s/n, 18016 Granada, Spain.ORCID 0000-0002-1944-7668
José Matías Triviño-JuárezDepartment of Radiology and Physical Medicine, Faculty of Medicine, University of Granada, Avenida Doctor Jesús Candel Fábregas 11, 18016 Granada, Spain.ORCID 0000-0002-0988-3191
María Jesús Álvarez-CuberoCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0002-5492-9355
Luis Javier Martínez-GonzálezCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0003-2202-0662
Cristina Lucía Dávila-FajardoCenter for Genomics and Oncological Research (GENYO), Pfizer-University of Granada-Junta de Andalucía, Avenida de la Ilustración 114, 18016 Granada, Spain.ORCID 0000-0003-3339-239X

Funding

Consejería de Universidad, Investigación e Innovación PY20_01155Ministerio de Ciencia, Innovación y Universidades PID2020-113823RB-I00/AEI/10.13039/501100011033
6 · The paper itself

Abstract

Clopidogrel is widely used as an antiplatelet therapy for acute coronary syndrome (ACS) patients undergoing percutaneous coronary intervention (PCI). Genetic factors influence variability in clopidogrel response, with non-functional

Indexed as

Acute Coronary SyndromeClopidogrelPercutaneous Coronary InterventionPlatelet Aggregation InhibitorsPolymorphism, Single NucleotideStentsAgedCytochrome P-450 CYP2C19FemaleGenotypeHumansMaleMiddle AgedClopidogrelCYP2C19 protein, humanCytochrome P-450 CYP2C19Platelet Aggregation Inhibitorsacute coronary syndromeatherosclerosiscardiovascular drugsclopidogrel responsedual antiplatelet therapypersonalized medicinepharmacogenomics

Identifiers

PMID41097034
PMCPMC12524468

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.