Evidence map›Paper›PMID 41097303›Full record

ArticleMolecules (Basel, Switzerland)2025

hERG Channel Blockade and Antagonistic Interactions of Three Steroidal Alkaloids from

Hui Lu, Tingting Hao, Zixuan Zhang, Chenxin Jiang, Jianwei Xu, Antony Stalin, Wei Zhao

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hui LuNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.
Tingting HaoNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.
Zixuan ZhangNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.
Chenxin JiangNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.
Jianwei XuNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.
Antony StalinInstitute of Fundamental and Frontier Sciences, University of Electronic Science and Technology of China, No. 4, Section 2, North Jianshe Road, Chengdu 610054, China.ORCID 0000-0002-2929-5936
Wei ZhaoNational Key Laboratory for Development and Utilization of Forest Food Resources, Zhejiang Agriculture and Forestry University, No. 666, Wusu Street, Hangzhou 311300, China.

Funding

National Natural Science Foundation of China 62472069Scientific Research Foundation of Zhejiang A & F University 2019FR027Zhejiang Provincial Natural Science Foundation LBY22H270002Zhejiang Provincial Natural Science Foundation LGF18H280002
6 · The paper itself

Abstract

The bulb of

Indexed as

AlkaloidsERG1 Potassium ChannelEther-A-Go-Go Potassium ChannelsFritillariaPotassium Channel BlockersSteroidsCevanesHEK293 CellsHumansMolecular Docking SimulationMolecular Dynamics SimulationPatch-Clamp TechniquesAlkaloidsCevanesERG1 Potassium ChannelEther-A-Go-Go Potassium ChannelsKCNH2 protein, humanpeimininePotassium Channel BlockersSteroidsalkaloidsBei MuFritillariahERGhERG-blockadeMD simulation

Identifiers

PMID41097303
PMCPMC12526275

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.