Evidence map›Paper›PMID 41097352›Full record

ArticleMolecules (Basel, Switzerland)2025

Ozone Saline Solution Polarizes Microglial Cells Towards an Anti-Inflammatory Phenotype.

Federica Armeli, Beatrice Mengoni, Martina Menin, Gregorio Martínez-Sánchez, Mauro Martinelli, Maurizio Maggiorotti, Rita Businaro

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecules (Basel, Switzerland), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Federica ArmeliDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-4981-3374
Beatrice MengoniDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0009-0005-5245-1684
Martina MeninDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0009-0003-0715-9401
Gregorio Martínez-SánchezIndependent Researcher, 60126 Ancona, Italy.ORCID 0000-0002-6628-7388
Mauro MartinelliOzone Therapy Unit, Department of Biomedical Sciences, Ospedale San Pietro Fatebenefratelli, 00189 Rome, Italy.ORCID 0009-0004-4547-686X
Maurizio MaggiorottiItalian College of Oxygen-Ozone Therapy (CIO3), 00186 Rome, Italy.ORCID 0009-0001-0474-1821
Rita BusinaroDepartment of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, 04100 Latina, Italy.ORCID 0000-0002-7890-8524

Funding

Sapienza University of Rome RM1241910D9FB1F1
6 · The paper itself

Abstract

Ozone (O

Indexed as

Anti-Inflammatory AgentsMicrogliaOzoneSaline SolutionAnimalsAntioxidantsCell LineCell ProliferationCell SurvivalHumansLipopolysaccharidesMiceNF-E2-Related Factor 2PhenotypeReactive Oxygen SpeciesSuperoxide Dismutase-1Anti-Inflammatory AgentsAntioxidantsLipopolysaccharidesNF-E2-Related Factor 2OzoneReactive Oxygen SpeciesSaline SolutionSuperoxide Dismutase-1anti-inflammatory responsecytokinesimmunomodulationmicrogliaNrf2ozonated saline solutionozone therapyreactive oxygen species

Identifiers

PMID41097352
PMCPMC12526464

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.