Evaluation of real-world follow-up methods and their association with adherence and safety in adjuvant breast cancer therapy: a retrospective study.

Aim: To compare the associations between different follow-up management methods-telephone, WeChat, and mini-program-and treatment compliance, safety, quality of life, and self-management in breast cancer patients receiving adjuvant therapy. Methods: This retrospective study reviewed clinical and follow-up records of patients with newly diagnosed breast cancer who underwent adjuvant therapy after radical surgery. Based on documented follow-up modes, patients were categorized into three groups: telephone, WeChat, and the "Doctor Haixin" mini-program. Key clinical indicators, including treatment adherence, quality of life, adverse events, and self-management levels, were extracted from medical records and patient-reported follow-up data collected over a 12-week period. Results: Patients in the mini-program group were found to have higher recorded adherence rates and better self-reported outcomes in quality of life and self-management compared with the telephone and WeChat groups. All groups showed improved quality of life over time, while adverse event rates remained comparable across groups. Conclusion: Among patients retrospectively assessed, those managed via the mini-program follow-up exhibited more favorable patterns in adherence and patient-reported outcomes. These findings suggest that digital platforms may be associated with enhanced care quality in the context of breast cancer follow-up.