Evidence mapPaperPMID 41100726Full record

ArticleMacromolecular rapid communications2026

Degradable Nanocarriers Capable of Gene Delivery Derived from pH-Responsive Polyester: RROP Copolymerization Between Cyclic Ketene Acetals.

Yiyi Deng, Jonas Debbeler, Anja Traeger, Jens Gaitzsch

Abstract read
In one paragraph

Article in Macromolecular rapid communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yiyi DengLeibniz-Institut Für Polymerforschung Dresden e.V., Dresden, Germany.ORCID https://orcid.org/0000-0002-8156-5067
Jonas DebbelerLaboratory of Organic and Macromolecular Chemistry, Friedrich Schiller University Jena, Jena, Germany.
Anja TraegerLaboratory of Organic and Macromolecular Chemistry, Friedrich Schiller University Jena, Jena, Germany.ORCID https://orcid.org/0000-0001-7734-2293
Jens GaitzschLeibniz-Institut Für Polymerforschung Dresden e.V., Dresden, Germany.ORCID https://orcid.org/0000-0002-8858-982X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability to combine biodegradability with responsive units by radical ring-opening polymerization (RROP) is the ideal setup for a modern drug delivery system. Since the required polymers were recently unlocked by RROP copolymerization between different cyclic ketene acetals (CKAs), we herein prepared a series of polyester copolymers derived from an amine-bearing CKA 6-(iso-propyl)-2-methylene-1,3,6-dioxazocane (

Indexed as

AcetalsDrug CarriersEthylenesGene Transfer TechniquesKetonesNanoparticlesPolyestersHydrogen-Ion ConcentrationParticle SizePolymerizationAcetalsDrug CarriersEthylenesketeneKetonesPolyestersbiodegradable polyesterscyclic ketene acetals (CKAs)gene deliverypH‐responsive nanoparticlesradical ring‐opening polymerization (RROP)

Identifiers

PMID41100726
PMCPMC13384792

What Socratic holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.