Evidence map›Paper›PMID 41101394›Full record

ReviewAdvances in nutrition (Bethesda, Md.)2025

Bioactives in Food-As-Medicine for Special Medical Purposes.

Xueyao Xi, Senyang Hu, Xunuo Zhang, Peng An, Yongting Luo, Junjie Luo, Yinhua Zhu

Abstract readReview
In one paragraph

Review in Advances in nutrition (Bethesda, Md.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueyao XiKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Senyang HuKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Xunuo ZhangKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China.
Peng AnKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China. Electronic address: an-peng@cau.edu.cn.
Yongting LuoKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China. Electronic address: luo.yongting@cau.edu.cn.
Junjie LuoKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China. Electronic address: luojj@cau.edu.cn.
Yinhua ZhuKey Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China. Electronic address: zhuyinhua@cau.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With rising global attention to health and the accelerating trend of population aging, the demand for Foods for Special Medical Purposes (FSMPs) has increased substantially. These products are formulated not only to meet the basic nutritional needs of individuals with specific diseases or physiological conditions but also to provide regulatory physiological effects. In this context, the "Food-As-Medicine" (FAM) concept has gained growing interest. FAM seeks to prevent and treat diseases through the incorporation of functional foods into health management strategies and aligns closely with the traditional Chinese medicine (TCM) theory of "Food-Medicine Homologous" (FMH). Guided by FMH principles, natural bioactive compounds such as polysaccharides, flavonoids, and saponins have drawn significant attention for their anti-inflammatory, antioxidant, and immunomodulatory properties. However, their broader application faces several challenges, including low extraction efficiency, complex purification procedures, and difficulties in ensuring stability, all of which hinder industrial-scale development. This review systematically explores the potential, challenges, and opportunities of FMH-based products in FSMPs, with a particular emphasis on infant nutrition, maternal health, and the management of chronic diseases in the elderly. Our findings highlight the dual value of FMH ingredients in both nutritional support and functional modulation. Furthermore, by integrating FMH theory with modern nutritional science, this review offers a scientific basis for the innovative development of FSMPs. Given the growing global market demand and the increasing dissemination of TCM culture, this field is poised to enter a new phase of development.

Indexed as

Functional FoodMedicine, Chinese TraditionalPhytochemicalsAntioxidantsChronic DiseaseFemaleFlavonoidsHumansInfantInfant Nutritional Physiological PhenomenaAntioxidantsFlavonoidsPhytochemicalsdisease managementFood-As-MedicineFood-Medicine HomologousFoods for Special Medical Purposeshealth promotionnutritional support

Identifiers

PMID41101394
PMCPMC12766056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.