Evidence map›Paper›PMID 41102316›Full record

ArticleNPJ digital medicine2025

Generalized multi task learning framework for glucose forecasting and hypoglycemia detection using simulation to reality.

Minjoo Hwang, Vega Pradana Rachim, Junyoung Yoo, Yein Lee, Sung-Min Park

Abstract read
In one paragraph

Article in NPJ digital medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

5 authors.

Minjoo HwangGraduate School of Artificial Intelligence, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.
Vega Pradana RachimDepartment of Convergence IT Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.
Junyoung YooDepartment of Convergence IT Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.
Yein LeeDepartment of Convergence IT Engineering, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea.
Sung-Min ParkGraduate School of Artificial Intelligence, Pohang University of Science and Technology (POSTECH), Pohang, Republic of Korea. sungminpark@postech.ac.kr.

Funding

Ministry of Science and ICT, South Korea RS-2019-II191906National Research Foundation of Korea RS-2024-00426901National Research Foundation of Korea RS-2025-00517742
6 · The paper itself

Abstract

Continuous prediction of glucose levels and hypoglycemia events is critical for managing type 1 diabetes mellitus (T1DM) under intensive insulin therapy. Existing models focus on a single task, limiting their practicality and adaptability in automated insulin delivery (AID) systems. To address this, a domain-agnostic continual multi-task learning (DA-CMTL) framework that simultaneously performs glucose level forecasting and hypoglycemia event classification within a unified framework is proposed. Trained on simulated datasets via Sim2Real transfer and adapted using elastic weight consolidation, DA-CMTL supports cross-domain generalization. Evaluation on public datasets (DiaTrend, OhioT1DM, and ShanghaiT1DM) yielded a root mean squared error of 14.01 mg/dL, mean absolute error of 10.03 mg/dL, and sensitivity/specificity of 92.13%/94.28% on 30 min prediction. Real-world validation using diabetes-induced rats demonstrated a reduction in time below range from 3.01% to 2.58%, supporting reliable integration as a safety layer in AID systems. These results highlight DA-CMTL's robustness, scalability, and potential to improve safety in AID.

Identifiers

PMID41102316
PMCPMC12531325

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.