Evidence map›Paper›PMID 41102721›Full record

Observational studyBMC pediatrics2025

Can PIM3 predict mortality adequately for patients admitted to Pediatric Intensive Care Unit in a resource limited setting? A single-center study.

Desy Rusmawatiningtyas, Renova Astriani Hutapea, Antonius H Pudjiadi, Firdian Makrufardi, Hennie Knoester, J B M van Woensel

Abstract readObservational Study
In one paragraph

Observational study in BMC pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Desy RusmawatiningtyasChild Health Department, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, 55281, Indonesia. desy.rusmawatiningtyas@ugm.ac.id.
Renova Astriani HutapeaChild Health Department, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, 55281, Indonesia.
Antonius H PudjiadiChild Health Department, Faculty of Medicine, Universitas Indonesia, Jakarta, Indonesia.
Firdian MakrufardiChild Health Department, Faculty of Medicine, Public Health, and Nursing, Universitas Gadjah Mada/Dr Sardjito General Hospital, Yogyakarta, 55281, Indonesia.
Hennie KnoesterDepartment of Pediatric Intensive Care, Emma Children's Hospital/Amsterdam University Medical Centers, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.
J B M van WoenselDepartment of Pediatric Intensive Care, Emma Children's Hospital/Amsterdam University Medical Centers, University of Amsterdam, Meibergdreef 9, Amsterdam, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Indonesia the number of critically ill children by far exceeds Pediatric Intensive Care Unit (PICU) capacity. A quantitative scoring system that can be used by clinicians from the initial encounter might be helpful as an objective assessment method to predict patient outcomes, thus aiding clinical decision-making, patient stratification and prioritization. The aim of this study was to assess the performance of the Paediatric Index of Mortality-3 (PIM3) score to predict mortality of critically ill pediatric referral patients that had been accepted and admitted to the PICU of Dr Sardjito General Hospital Yogyakarta.

methodsThis retrospective observational cohort study included patients from August 1st, 2022 -January 31st, 2023 who were referred and admitted to the PICU of Dr. Sardjito General hospital, Yogyakarta, Indonesia. The discriminative ability (to differentiate between survivors and non survivors) of PIM3 scoring system was analyzed with the area under the receiver-operating characteristic curve (AUC).

resultsA total of 220 cases (median age 64 (1-215) months) were included. The overall mortality rate was 22.1% (49/220). Subjects’ PIM3 score ranged from 0.11 to 98.03. The Standardized Mortality Ratio (SMR) of PIM3 with 95% confidence interval (CI) was 2.23 (1.65–2.90). The AUC with 95%-CI was 0.84 (0.77–0.91, p < 0.001). The difference between observed and predicted mortality by PIM3 was statistically significant, indicating that actual mortality was higher than PIM3 predicted.

conclusionAmong critically ill children who were referred form peripheral hospitals and admitted to PICU at Dr Sardjito General Hospital, PIM3’s discrimination was good, but the calibration was poor, indicating that PIM3 was unfitted as mortality predictor in this study population.

Indexed as

Critical IllnessHospital MortalityIntensive Care Units, PediatricSeverity of Illness IndexAdolescentChildChild, PreschoolFemaleHumansIndonesiaInfantMalePredictive Value of TestsResource-Limited SettingsRetrospective StudiesROC CurveMortalityPediatricPediatric Intensive Care UnitPIM3 score

Identifiers

PMID41102721
PMCPMC12532814

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.