Evidence mapPaperPMID 41103268Full record

SynthesisBJOG : an international journal of obstetrics and gynaecology2026

Interventions to Improve Outcomes After Pregnancy Loss: A Systematic Review.

Becky MacGregor, Samuel Madejowski, Helen Leach, Clare Macdonald, Jeremy Dale, Amy Grove, Alexander E P Heazell, Jo Parsons, Sophie Staniszewska, Sarah Hillman

Abstract readSystematic Review
In one paragraph

Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Becky MacGregorApplied Health Sciences, University of Birmingham, Birmingham, UK.ORCID https://orcid.org/0000-0002-9530-8387
Samuel MadejowskiWarwick Medical School, University of Warwick, Coventry, West Midlands, UK.
Helen LeachWarwick Applied Health, University of Warwick, Coventry, West Midlands, UK.
Clare MacdonaldApplied Health Sciences, University of Birmingham, Birmingham, UK.
Jeremy DaleWarwick Applied Health, University of Warwick, Coventry, West Midlands, UK.
Amy GroveSchool of Social Policy and Society, University of Birmingham, Birmingham, UK.
Alexander E P HeazellMaternal and Fetal Health Research Centre, University of Manchester, Manchester, UK.ORCID https://orcid.org/0000-0002-4303-7845
Jo ParsonsSchool of Social Policy and Society, University of Birmingham, Birmingham, UK.
Sophie StaniszewskaWarwick Applied Health, University of Warwick, Coventry, West Midlands, UK.
Sarah HillmanApplied Health Sciences, University of Birmingham, Birmingham, UK.

Funding

National Institute for Health and Care Research NIHR303237
6 · The paper itself

Abstract

backgroundStillbirth, second-trimester miscarriage and recurrent miscarriage carry significant consequences for women. We lack sufficient high-quality evidence of interventions to improve a woman's health and subsequent pregnancy outcomes after discharge to the community.

objectiveAssess the effectiveness of interventions to improve general health and subsequent pregnancy outcomes for non-pregnant women who have had a stillbirth, second trimester miscarriage, or recurrent miscarriage. SEARCH STRATEGY: Database searches were undertaken in August 2022 (updated March 2024) and limited to full-text documents published from 1995. SELECTION CRITERIA: Interventions delivered after discharge for non-pregnant women following a pregnancy loss. DATA COLLECTION AND ANALYSIS: Screening was performed independently by two reviewers; narrative synthesis was undertaken. Risk of bias was assessed by RoB-2, ROBINS-I or the Mixed Methods Appraisal Tool. MAIN

resultsA total of 18 603 abstracts screened; 196 full texts assessed and 15 papers included. The quality of evidence was low, and the primary aim of the review was not met due to limited evidence. All included studies aimed to improve mental health. No studies were identified that aimed to improve the physical health of women or subsequent pregnancy outcomes.

conclusionsThere is a significant evidence gap regarding how best to care for women who experience pregnancy loss after discharge to the community. There is an urgent need for research to determine which interventions are most effective to improve a woman's short- and long-term health and subsequent pregnancy outcomes following a stillbirth, second-trimester miscarriage or recurrent miscarriage.

trial registrationPROSPERO Registration: CRD42022360264.

Indexed as

Abortion, HabitualAbortion, SpontaneousStillbirthFemaleHumansPregnancyPregnancy OutcomePregnancy Trimester, Secondbereavement counsellingmiscarriagepuerperiumrecurrentsystematic reviews

Identifiers

PMID41103268
PMCPMC12770074

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.