Evidence map›Paper›PMID 41103685›Full record

ArticleBiochemia medica2025

Preanalytical mystery: falsely elevated intact parathyroid hormone due to sampling from a grafted forearm.

Yu-Wei Tseng, Chun-Chieh Yeh, Che-Yi Chou, Si-Yu Chen, Tze-Kiong Er

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemia medica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yu-Wei TsengDivision of Laboratory Medicine, Asia University Hospital, Asia University, Taichung, Taiwan.
Chun-Chieh YehDepartment of Surgery, Asia University Hospital, Taichung, Taiwan.
Che-Yi ChouDivision of Nephrology, Asia University Hospital, Taichung, Taiwan.
Si-Yu ChenDivision of Laboratory Medicine, Asia University Hospital, Asia University, Taichung, Taiwan.
Tze-Kiong ErDivision of Laboratory Medicine, Asia University Hospital, Asia University, Taichung, Taiwan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spurious elevations in intact parathyroid hormone (iPTH) can lead to unnecessary interventions. We describe a dialysis patient who developed unexpectedly high iPTH concentrations months after total parathyroidectomy with forearm autotransplantation (TPTX-AT). Blood samples had been collected from the grafted forearm, resulting in falsely elevated iPTH values. Once the sample was collected from the non-grafted arm, iPTH concentrations normalized. This case highlights the importance of sampling site awareness in laboratory diagnostics and demonstrates how implementing a simple laboratory information system (LIS)-based protocol can prevent misinterpretation.

Indexed as

Blood Specimen CollectionForearmParathyroid HormoneFalse Positive ReactionsHumansParathyroidectomyRenal DialysisTransplantation, AutologousParathyroid Hormonecase reportiPTH, sampling siteparathyroid autotransplantationpreanalytical error

Identifiers

PMID41103685
PMCPMC12523601

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.