ReviewHealth science reports2025
The Impact of Melatonin Supplementation on Various Aspects of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.
Review in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Role of Antioxidants in the Management of Polycystic Ovary Syndrome.Antioxidants (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background and Aims: Polycystic ovary syndrome (PCOS) is a prevalent gynecological condition affecting women of reproductive age, with implications for multiple aspects of women's health. Recent research indicates that melatonin (MLT) may enhance several dimensions of this syndrome via various mechanisms. Consequently, this study was undertaken to systematically evaluate the impact of MLT supplementation on different aspects of PCOS. Methods: According to the PRISMA guideline, we identified studies published between January 2013 and November 4, 2024, through a comprehensive electronic search of several reputable databases, including Web of Science (WoS), PubMed (MEDLINE), ProQuest, Scopus, and Google Scholar, utilizing MESH keywords. A meta-analysis was conducted employing a random-effects model, during which we computed the standardized mean differences (SMDs) along with their corresponding 95% confidence intervals. Results: A total of 12 studies were incorporated into the meta-analysis, encompassing 1590 women diagnosed with PCOS. Among these participants, 710 were assigned to the intervention group, while 692 were placed in the comparison or control group, representing data collected from six countries. The SMD for total antioxidant capacity (TAC), and endometrial thickness were 0.97 [95% CI 0.55; 1.40, Conclusion: The administration of an appropriate dose of MLT demonstrates a notable impact on TAC, endometrial thickness, and the clinical pregnancy rate. This intervention may assist women with PCOS in effectively addressing the challenges associated with this condition, complementing standard treatment protocols.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.