Evidence mapPaperPMID 41107549Full record

ReviewNature reviews. Neuroscience2025

Glia of the heart's nervous system.

Katharina Scherschel, Hanna Wolf, Olujimi A Ajijola, Kalyanam Shivkumar, Diana Lindner, Jose A Gomez-Sanchez, Christian Meyer

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Neuroscience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Katharina ScherschelDivision of Cardiology, Angiology and Intensive Care, EVK Düsseldorf, cNEP, Cardiac Neuro- and Electrophysiology Research Consortium, Düsseldorf, Germany. katharina.scherschel@hhu.de.ORCID http://orcid.org/0000-0002-3237-140X
Hanna WolfDepartment of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
Olujimi A AjijolaDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Kalyanam ShivkumarDavid Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.
Diana LindnerDepartment of Cardiology and Angiology, University Heart Center Freiburg-Bad Krozingen - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-5477-769X
Jose A Gomez-SanchezInstituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Alicante, Spain.
Christian MeyerDivision of Cardiology, Angiology and Intensive Care, EVK Düsseldorf, cNEP, Cardiac Neuro- and Electrophysiology Research Consortium, Düsseldorf, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The heart adapts to changing physiological demands through bidirectional interactions with the brain. These are mediated via extensive feedback loops of the cardiac autonomic nervous system, a complex network of neurons and glial cells. Although the presence of glia in the heart and its nervous system has been known for decades, only recently has an understanding of their contribution to cardiac physiology and pathophysiology emerged. As new types of cardiac glia are discovered, it becomes evident that they represent heterogeneous cell populations in distinct anatomical locations of the cardiac nervous system, contributing not only to autonomic control of the healthy heart but also to pathological changes in the diseased heart.

Indexed as

Autonomic Nervous SystemHeartNeurogliaAnimalsHumans

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.