Evidence map›Paper›PMID 41107599›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025

Patient-, care partner-, and clinician-proposed solutions to address the time toxicity of cancer care.

Whitney V Johnson, Sai S Valisekka, Obafemi O Ogunleye, Samuel X Stevens, Manju George, Allison Breininger, Michael Anne Kyle, Christopher M Booth, Timothy P Hanna, Rachel I Vogel and 3 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Cancer patients' experiences of "time toxicity": a qualitative meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  2. Experiences and coping strategies of time toxicity in young and middle-aged patients with lymphoma: a descriptive qualitative study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  3. Article
  4. The experience of time toxicity in cancer patients: a meta-synthesis of qualitative research.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Review
  5. Healthcare contact days in cancer survivors relative to those with no cancer history.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Whitney V Johnson *University of Minnesota, MN, Minneapolis, USA.
Sai S Valisekka *University of Minnesota, MN, Minneapolis, USA.
Obafemi O OgunleyeUniversity of Minnesota, MN, Minneapolis, USA.
Samuel X StevensSchool of Medicine, The University of Sydney, Camperdown, Australia, NSW.
Manju GeorgePaltown Development Foundation/COLONTOWN, Edgewater, MD, USA.
Allison BreiningerThe Negative Space, Minneapolis, USA, MN.
Michael Anne KyleUniversity of Pennsylvania, Department of Medical Ethics and Health Policy, Philadelphia, USA, PA.
Christopher M BoothSinclair Cancer Research Institute, Division of Cancer Care and Epidemiology, Kingston, ON, Canada.
Timothy P HannaSinclair Cancer Research Institute, Division of Cancer Care and Epidemiology, Kingston, ON, Canada.
Rachel I VogelUniversity of Minnesota, MN, Minneapolis, USA.
Helen M ParsonsUniversity of Minnesota, MN, Minneapolis, USA.
Anne H BlaesUniversity of Minnesota, MN, Minneapolis, USA.
Arjun GuptaUniversity of Minnesota, MN, Minneapolis, USA. arjgupta@umn.edu.

Funding

Women's CancerP30CA077598 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Jeffrey S. Miller · 1998 to 2026
$100.4M
Patient Administrative Burden in Cancer Care DeliveryR00CA277367 · NCI · UNIVERSITY OF PENNSYLVANIA · PI Michael Anne Kyle · 2024 to 2026
$747k
American Cancer Society Institutional Research Grant #129819-IRG-21-049-61-IRG138NCI NIH HHS P30 CA077598NCI NIH HHS R00 CA277367
6 · The paper itself

Abstract

purposeAs the concept of time toxicity has gained traction in the oncology community, work has largely focused on mapping and measuring time burdens. This qualitative study sought to elicit perspectives from people with lived or professional experience with cancer care on strategies to decrease the time burden of oncology care.

methodsWe conducted semi-structured interviews with 47 participants (16 patients with advanced gastrointestinal cancer, 15 of informal care partners, and 16 oncology clinicians with diverse roles) from a single academic cancer center in Minneapolis, Minnesota. Interviews were conducted between February 2023 and October 2023 and transcribed and analyzed using a hybrid approach.

resultsFive key themes emerged as solutions to address time toxicity: (1) tailored ambulatory scheduling based on patient and care partner needs; (2) improved administrative and logistical support; (3) home-based care when safe, feasible, and preferred; (4) transparent and empathetic communication of time demands, and (5) innovative care models and delivery. Participants emphasized that the threshold between helpful and burdensome care in the context of a cancer diagnosis differs for each person, requiring individualized solutions.

conclusionFindings from this study will aid the oncology community in considering and designing interventions to decrease the time burdens of cancer care on patients and their care partners. Implementing changes to meet the need for individualized, person-centered interventions, focusing on individuals' preferences and unique circumstances, will require health system will and motivation .

Indexed as

CaregiversGastrointestinal NeoplasmsAdultAgedCommunicationFemaleHome Care ServicesHumansInterviews as TopicMaleMiddle AgedMinnesotaQualitative ResearchTime FactorsCancerCare deliveryCare partnersHealth system navigationQuality of lifeTime burdensTime toxicity

Identifiers

PMID41107599
PMCPMC12534262

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.