ReviewEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2026
Application value and performance of stool antigen detection in the diagnosis of Helicobacter pylori infection.
Review in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Myco-synthesized silver nanoparticles from Aspergillus niger AH1 as multifunctional anti-Helicobacter pylori agents: Antibacterial, antibiofilm, anti-urease, and antibiotic-synergistic activities.Folia microbiologica · 2026Article
- Fecal miR-146a as a Non-Invasive Biomarker forLife (Basel, Switzerland) · 2026Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
purposeHelicobacter pylori infection is associated with various digestive disorders, including chronic gastritis, peptic ulcers, gastric mucosa-associated lymphoid tissue lymphoma, and gastric cancer, posing significant risks to human health. Effective and timely detection of H. pylori is crucial for early intervention and prevention. This review aims to evaluate the sensitivity and specificity of stool antigen detection and assess its clinical application value.
methodsWe conducted a comprehensive review of the literature focusing on studies that compared invasive and non-invasive diagnostic methods for H. pylori, with an emphasis on stool antigen tests. Data on diagnostic performance, including sensitivity, specificity, advantages, and limitations, were synthesized from recent clinical evaluations and meta-analyses.
resultsStool antigen detection demonstrates high diagnostic accuracy, with sensitivity and specificity often exceeding 90%, particularly when monoclonal antibody-based tests are used. It offers a non-invasive, cost-effective alternative to urea breath tests and is applicable across diverse populations, including children and the elderly. However, factors such as sample handling, antigen stability, and bacterial load can influence results.
conclusionStool antigen testing is a reliable tool for the initial diagnosis and post-treatment monitoring of H. pylori infection. Its high performance and practicality support its use in clinical practice, especially in settings where endoscopy or breath testing is less feasible. Further standardization and technological advances may enhance its utility in global screening programs.
Indexed as
Identifiers
41108436What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.