Evidence map›Paper›PMID 41108446›Full record

ReviewCurrent neurology and neuroscience reports2025

Frontal Disorders and Consciousness: A Review.

Joshua G Berenbaum, Benjamin Morrison, Brenna Hagan, Kathy Y Xie, Katherine W Turk, Andrew E Budson

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current neurology and neuroscience reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects ofFrontiers in nutrition · 2026
    Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Joshua G BerenbaumCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA. jberenb1@bu.edu.ORCID http://orcid.org/0009-0002-1440-4535
Benjamin MorrisonCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA.
Brenna HaganCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA.ORCID http://orcid.org/0009-0004-7830-0780
Kathy Y XieCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA.
Katherine W TurkCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA.ORCID http://orcid.org/0000-0002-6833-5494
Andrew E BudsonCenter for Translational Cognitive Neuroscience, VA Boston Healthcare System (12C), 150 S Huntington Avenue, Boston, MA, 02130, USA. abudson@bu.edu.ORCID http://orcid.org/0000-0002-2913-0015

Funding

RL5: Research Education CoreP30AG072978 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Ann C. McKee · 2021 to 2026
$25.6M
CSRD VA I01 CX002400NIA NIH HHS P30AG072978U.S. Department of Veterans Affairs I01CX002400
6 · The paper itself

Abstract

purpose of reviewThe frontal cortex plays a key role in many functions considered to be relevant for consciousness. Furthermore, altered consciousness appears to exist in those with disorders that disrupt or damage frontal areas and/or networks. This article reviews recent research discussing the impact of frontal disorders on consciousness. RECENT

findingsMany theories of consciousness have been developed over the last century to help explain the neural correlates of consciousness. Some theories argue that the frontal cortex is necessary for consciousness, while others argue that posterior cortical regions are critical for consciousness. The Memory Theory of Consciousness argues that consciousness requires modality-specific localization throughout the brain. We argue that frontal disorders do not abolish consciousness but they may disrupt conscious abilities such as sustained attention, working memory, problem-solving, complex thought, executive function, response inhibition, decision-making, and goal-oriented behavior. Understanding the role of the frontal cortex in consciousness has significant scientific, clinical, and societal implications.

Indexed as

ConsciousnessConsciousness DisordersFrontal LobeHumansConsciousnessDementiaFrontal disordersMemoryMemory theory of consciousnessPrefrontal cortex

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.