ArticleJournal of endocrinological investigation2026
Primary hyperparathyroidism incidence in northeastern Italy: A large population-based study.
Article in Journal of endocrinological investigation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposePopulation-based studies of trends in the incidence of primary hyperparathyroidism (PHPT) in Italy were still lacking. Our aim was to estimate the incidence of PHPT in the Veneto region over the period 2012–2023.
methodsA retrospective, population-based study conducted in Veneto using the population registry and administrative health databases. Only subjects ≥ 18 years of age were included. We documented incident PHPT from 2013 to 2023 to exclude prevalent cases and calculated standardised incidence rates (IR) per 10,000 person-years by age and sex. We also made a sub analysis of only surgical cases.
resultsWe identified 5,276 incident cases (IR: 1.17). Overall, the incidence of PHPT was stable from 2013 to 2023, although there was a declining trend in males, at the limits of statistical significance with the standardised IR decreasing from 0.77 (95% CI: 0.64;0.91) in 2013 to 0.67 in 2023 (95% CI: 0.55;0.78) (p = 0.056). The overall female-to-male incidence ratio was 2.55, with females predominating, and reached a peak in the 50–54 age group (ratio: 3.94) and a nadir in 25–29 age group (ratio: 0.54). Median age was 65 years (IQR: 56–76 years) and was lower among females than males (64 vs 68 years) (p < 0.0001). Among the surgical cases, the percentage distribution of incident cases by age was almost the same for females and males, median age was similar (61 years for females, 62 years for males), while the rates remained higher for females than for males.
conclusionOur study shows that over the past decade there has been a general stability in the incidence of PHPT in our Region. A higher incidence was observed in postmenopausal females and a different pattern of incidence emerged from our analysis of surgical cases.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.