Evidence map›Paper›PMID 41109648›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance

Accurate myocardial T1 mapping at 5T using an improved modified Look-Locker inversion recovery method: A validation study.

Linqi Ge, Yinuo Zhao, Yubo Guo, Yuanyuan Liu, Yihang Zhou, Haifeng Wang, Dong Liang, Hairong Zheng, Yining Wang, Yanjie Zhu

Abstract readValidation StudyMulticenter Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Simultaneous myocardial T1, T2, T1ρ and fat fraction mapping with hybrid dual-echo cartesian acquisition and dictionary matching.Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Linqi GePaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; University of Chinese Academy of Sciences, Beijing, China.
Yinuo ZhaoPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Yubo GuoDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Yuanyuan LiuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Yihang ZhouState Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; Research Center for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Haifeng WangPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Dong LiangState Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; Research Center for Medical AI, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Hairong ZhengPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China.
Yining WangDepartment of Radiology, State Key Laboratory of Complex Severe and Rare Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address: wangyining@pumch.cn.
Yanjie ZhuPaul C. Lauterbur Research Center for Biomedical Imaging, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China; State Key Laboratory of Biomedical Imaging Science and System, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, Guangdong, China. Electronic address: yj.zhu@siat.ac.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAccurate myocardial T1 mapping at 5T remains a technical challenge due to field inhomogeneity and prolonged T1 values. The aim of this study was to develop an accurate and clinically applicable myocardial T1 mapping technique for 5T magnetic resonance imaging systems and validate its performance in a multicenter study.

methodsThe proposed method is based on a 5-(3)-3 modified Look-Locker inversion recovery (MOLLI) sequence, dubbed combined-correction MOLLI (coMOLLI), which corrects for both inversion efficiency and readout-induced signal disturbances. Specifically, coMOLLI employs a radiofrequency spoiled gradient recalled echo (GRE) readout rather than the commonly used balanced steady state free precession (bSSFP) readout. Its signal evolution is modeled to estimate T1 values, which incorporates both inversion efficiency and readout disturbances to improve fitting accuracy. To further enhance accuracy, the inversion pulse was redesigned under hardware constraints and the observed B

resultsThe optimized inversion pulse at 5T is the Tan/Tanh pulse with A = 10 kHz, K

conclusionThe coMOLLI method demonstrated high accuracy in phantom studies and feasibility in vivo studies. By adopting the widely used 5-(3)-3 MOLLI acquisition scheme, it shows potential for clinical cardiac imaging at 5T.

Indexed as

Image Interpretation, Computer-AssistedMagnetic Resonance ImagingMyocardiumAdultFemaleHumansMaleMiddle AgedPhantoms, ImagingPredictive Value of TestsReproducibility of Results5TCoMOLLIImproved MOLLIMyocardial T1 mapping

Identifiers

PMID41109648
PMCPMC13199967

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.