ArticleFrontiers in cardiovascular medicine2025
Can computational fluid dynamics simulations predict a distal stent graft-induced new entry after frozen elephant trunk operation?
Article in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Computational fluid dynamics analysis for enlargement of the descending aorta after frozen elephant trunk implantation.Journal of cardiothoracic surgery · 2026Article
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Authors and funding
7 authors.
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Abstract
Objectives: Distal stent graft-induced new entry (dSINE) is a complication after frozen elephant trunk (FET) procedure. The purpose of this study was to identify the hemodynamic profile of the aorta associated with dSINE development using computational fluid dynamics (CFD) simulation. Methods: 30 patients, 15 who had developed a dSINE (dSINE group) and 15 without any further vascular events (control group), undergoing an FET operation for aortic dissection were retrospectively included in this CFD study. Patient-specific 3D surface models of the aortic lumen were reconstructed from computed tomography angiographic (CTA) datasets, utilizing the CTA acquired before dSINE onset. Steady-state CFD simulations were performed with laminar blood flow and zero-pressure outlet conditions to assess velocity magnitudes, wall shear stress (WSS), and vorticity within the stent graft (SG), its distal landing zone and further downstream. Results: In the dSINE group, WSS was significantly elevated distal to the SG compared to WSS within the SG and at its landing (2.95 ± 1.47 Pa vs. 1.56 ± 0.71 Pa and 2.00 ± 0.81 Pa, Conclusions: Increased WSS distal to the SG compared to within the SG and its landing zone seem to be associated with dSINE development. CFD can be a useful tool to understand SG-induced hemodynamic changes in the aorta to help predict complications after FET.
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