Evidence map›Paper›PMID 41112805›Full record

ArticleBiomedical optics express2025

Megahertz dynamic optical coherence tomography of blisters in human skin.

Madita Göb, Linh Ha-Wissel, Caren Jacobi, Jennifer E Hundt, Robert Huber

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madita GöbInstitute of Biomedical Optics, Universität zu Lübeck, Peter-Monnik-Weg 4, 23562 Lübeck, Germany.ORCID https://orcid.org/0000-0002-5992-9274
Linh Ha-WisselKlinik für Dermatologie, Allergologie und Venerologie, Universitätsklinikum Schleswig-Holstein (UKSH) Campus Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Caren JacobiLübecker Institut für Experimentelle Dermatologie (LIED), Universität zu Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Jennifer E HundtLübecker Institut für Experimentelle Dermatologie (LIED), Universität zu Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.
Robert HuberInstitute of Biomedical Optics, Universität zu Lübeck, Peter-Monnik-Weg 4, 23562 Lübeck, Germany.ORCID https://orcid.org/0000-0001-9785-6574

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Detecting epidermal blisters in human skin using optical coherence tomography (OCT) is clinically valuable, particularly for diagnosing autoimmune blistering diseases. Dynamic OCT (dOCT) extends conventional structural imaging by providing motion-based contrast sensitive to tissue dynamics. In this study, we analyze the diagnostic potential of dynamic contrast in high-speed (MHz-OCT) and microscopic (mOCT) OCT for blister imaging. We first evaluate whether these systems offer sufficient structural detail for blister detection, comparing them to a clinical reference. Dynamic contrast was then examined in an

Identifiers

PMID41112805
PMCPMC12532343

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.