Evidence map›Paper›PMID 41113003›Full record

ArticleAmerican journal of translational research2025

Risk factors for lumbar fascial edema in patients with osteoporotic vertebral compression fractures and its effect on residual pain after percutaneous vertebroplasty.

Nini Li, Yang Lu, Yuping Zhang

Abstract read
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Article in American journal of translational research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Nini LiDepartment of Otolaryngology, Xi'an Central Hospital Xi'an 710003, Shaanxi, China.
Yang LuFirst Department of Orthopedic, Xi'an Central Hospital Xi'an 710003, Shaanxi, China.
Yuping ZhangFirst Department of Orthopedic, Xi'an Central Hospital Xi'an 710003, Shaanxi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo identify risk factors for lumbar fascial edema (LFE) in patients with osteoporotic vertebral compression fractures (OVCF) and evaluate its impact on residual pain after percutaneous vertebroplasty (PVP).

methodsA retrospective analysis was conducted on 360 OVCF patients who underwent PVP from January 2020 to March 2025. Based on MRI findings, patients were categorized into the LFE group (n=131) and non-LFE group (NLFE; n=229). Univariate and multivariate logistic regression analyses were used to identify independent risk factors, and receiver operating characteristic (ROC) curve analysis was used to assess their diagnostic value. Clinical parameters, including the presence or absence of edema, numerical rating scale (NRS) pain score, modified Oswestry disability index (ODI), C-reactive protein (CRP) and interleukin-6 (IL-6) levels, and postoperative residual pain were compared between patients in different age groups.

resultsMultivariate analysis identified age, history of trauma, presence of lumbar instability, and old vertebral compression fractures as independent risk factors for LFE (P<0.05). ROC curve analysis confirmed their significant diagnostic value. Compared with the NLFE group, the LFE group had significantly higher NRS and ODI scores, residual pain incidence, CRP, and IL-6 levels (P<0.05). Patients aged ≥70 years had significantly higher values for these parameters than those <70 years (P<0.05).

conclusionAdvanced age, trauma history, lumbar instability, and old vertebral compression fractures are significant risk factors for LFE in OVCF patients. The presence of LFE is associated with a higher incidence of postoperative residual pain.

Indexed as

inflammatory factorslumbar fascial edemaOsteoporotic vertebral compression fractureresidual painvertebroplasty

Identifiers

PMID41113003
PMCPMC12531560

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.