Evidence mapPaperPMID 41113628Full record

ArticleFrontiers in microbiology2025

Comprehensive molecular and phenotypic profiling of uropathogenic

Bryan Ortiz, Manuel G Ballesteros-Monrreal, Celeste Galindo, Daniel Rivera, Luis Rivera, Fernando Pérez, Victoria Maldonado, Elixia Valle, Ana Estrada, Pablo Mendez-Pfeiffer and 3 more

Abstract read
In one paragraph

Article in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Bryan Ortiz *Instituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Manuel G Ballesteros-Monrreal *Departamento de Ciencias Químico-Biológicas y Agropecuarias, Universidad de Sonora, Hermosillo, Mexico.
Celeste GalindoInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Daniel RiveraInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Luis RiveraInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Fernando PérezInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Victoria MaldonadoInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Elixia ValleInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Ana EstradaInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Pablo Mendez-PfeifferDepartamento de Ciencias Químico-Biológicas y Agropecuarias, Universidad de Sonora, Hermosillo, Mexico.
Lourdes EnríquezInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.
Dora ValenciaDepartamento de Ciencias Químico-Biológicas y Agropecuarias, Universidad de Sonora, Hermosillo, Mexico.
Gustavo FontechaInstituto de Investigaciones en Microbiología, Facultad de Ciencias, Universidad Nacional Autónoma de Honduras, Tegucigalpa, Honduras.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Urinary tract infections (UTIs) are a major public health concern, further complicated by the rise of multidrug-resistant bacterial strains. Uropathogenic Methods: This study conducted a comprehensive phenotypic and molecular characterization of 126 UPEC strains isolated from a tertiary care hospital in Tegucigalpa, Honduras. Seventeen virulence genes were screened, antimicrobial susceptibility to 17 antibiotics was assessed, phylogenetic grouping was performed, and potential clonal relationships were analyzed using ERIC-PCR. Results: Strains isolated from male patients exhibited significantly higher virulence gene counts (mean: 10.48 vs. 8.06; Discussion: This study provides the first in-depth molecular and phenotypic characterization of UPEC in Honduras. The detection of highly virulent and multidrug-resistant strains underscores the need to reinforce local molecular surveillance and to revise empirical treatment guidelines based on local epidemiological data.

Indexed as

HondurasUPEC resistanceUPEC virulenceurinary infectionUropathogenic Escherichia coli (UPEC)

Identifiers

PMID41113628
PMCPMC12528171

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.