Evidence map›Paper›PMID 41113632›Full record

ReviewFrontiers in microbiology2025

Detecting antibiotic resistance: classical, molecular, advanced bioengineering, and AI-enhanced approaches.

Alexandru Constantin Aldea, Filofteia Camelia Diguṭă, Oriana Presacan, Cătălina Voaideṣ, Radu Cristian Toma, Florentina Matei

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Antibiotic resistance inFrontiers in microbiology · 2026
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alexandru Constantin AldeaFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania.
Filofteia Camelia DiguṭăFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania.
Oriana PresacanFaculty of Electronics, Telecommunications, and Information Technology, National University of Science and Technology Politehnica Bucharest, Bucharest, Romania.
Cătălina VoaideṣFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania.
Radu Cristian TomaFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania.
Florentina MateiFaculty of Biotechnologies, University of Agronomic Sciences and Veterinary Medicine of Bucharest, Bucharest, Romania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Antibiotic resistance continues to erode the effectiveness of modern medicine, creating an urgent demand for rapid and reliable diagnostic solutions. Conventional diagnostic approaches, including culture-based susceptibility testing, remain the clinical reference standard but are constrained by lengthy turnaround times and limited sensitivity for early detection. In recent years, significant progress has been made with molecular and spectrometry-based methods, such as PCR and next-generation sequencing, MALDI-TOF MS, Raman and FTIR spectroscopy, alongside emerging CRISPR-based platforms. Complementary innovations in biosensors, microfluidics, and artificial intelligence further expand the diagnostic landscape, enabling faster, more sensitive, and increasingly portable assays. This review examines both established and emerging technologies for detecting antibiotic resistance, outlining their respective strengths, limitations, and potential roles across diverse settings. By synthesizing current advances and highlighting future opportunities, this review emphasizes complementarities among detection strategies and their potential integration into practical diagnostic frameworks, including in resource-limited settings.

Indexed as

antibiotic resistanceartificial intelligencedetection methodsESKAPEmachine learningmultidrug resistancenanotechnological platformspathogens

Identifiers

PMID41113632
PMCPMC12531165

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.