ReviewPsychopharmacology2026
The lateral habenula as a master regulator of innate and learned social behaviors.
Review in Psychopharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Serotonin deficiency caused by inactivation of Tph2 in mice leads to widespread sex-dependent changes in cerebral oxidative metabolic activity.Journal of neural transmission (Vienna, Austria : 1996) · 2026Article
- Whole-Brain Mapping of Neuronal Activity Associated with Vocal Socialization Behaviors in Adult Mice.eNeuro · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
Abstract
The lateral habenula (LHb) is classically associated with processing aversive stimuli and suppressing reward-driven behavior. Recent work, however, redefines the LHb as a node that not only mediates antisocial and avoidant behaviors but also regulates prosocial engagement and social motivation. As a convergence point for forebrain inputs and a driver of midbrain output, we review how the LHb contributes to behavioral outcomes in aggression, social avoidance, caregiving, and social memory. Cell-type-specific investigations reveal that glutamatergic (vGlut2⁺) and GABAergic (GAD2⁺) LHb neurons play dissociable roles in shaping aggression, social avoidance, and social cognition, while serotonin 2c receptor (5-HT
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.