Evidence map›Paper›PMID 41115237›Full record

ArticleJMIR medical informatics2025

Rapid Liver Fibrosis Evaluation Using the UNet-ResNet50-32 × 4d Model in Magnetic Resonance Elastography: Retrospective Study.

Pei-Yuan Su, Han-Jie Shih, Jia-Lang Xu

Abstract read
In one paragraph

Article in JMIR medical informatics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Pei-Yuan SuDepartment of Internal Medicine, Division of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0000-0002-6860-1051
Han-Jie ShihDepartment of Medical Imaging, Changhua Christian Hospital, Changhua, Taiwan.ORCID 0009-0007-4758-2713
Jia-Lang XuDepartment of Applied Statistics, National Taichung University of Science and Technology, No. 129, Section 3, Sanmin Road, North District, Taichung, 404336, Taiwan, 886 4-2219-6076, 886 4-2219-6330.ORCID 0000-0002-8052-9419

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Liver fibrosis is a pathological outcome of chronic liver injury and a hallmark of multiple chronic liver diseases. Magnetic resonance elastography (MRE) provides a non-invasive modality for evaluating the severity of liver fibrosis. Objective: This study aimed to develop and evaluate deep learning-based segmentation models for the automated assessment of liver fibrosis using MRE images, with a focus on comparing the performance of a conventional U-Net model and a UNet-ResNet50-32 × 4d architecture model. Methods: A retrospective analysis was conducted on 319 patients enrolled between January 2018 and December 2020. MRE images were processed and segmented using two U-Net-based models. Model performance was assessed through correlation coefficients, intersection over union (IoU), and additional segmentation metrics. Results: The UNet-ResNet50-32 × 4d model demonstrated strong agreement with ground truth annotations, achieving correlation coefficients of 0.952 in the training phase and 0.943 in the validation phase, along with an Dice score of 85.68%, confirming its high segmentation accuracy. Conclusions: The UNet-ResNet50-32 × 4d model exhibited robust performance and may serve as a reliable tool for the rapid and accurate assessment of liver fibrosis severity. The integration of automated segmentation into MRE analysis has the potential to improve clinical workflows and support timely decision-making in the management of chronic liver disease.

Indexed as

Deep LearningElasticity Imaging TechniquesLiver CirrhosisAdultAgedFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedRetrospective Studiesautomated segmentationimage segmentationliver fibrosismagnetic resonance elastographyMRI elastographytimely decision-making

Identifiers

PMID41115237
PMCPMC12538025

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.