Evidence map›Paper›PMID 41115946›Full record

ArticleRadiologie (Heidelberg, Germany)2025

[Options in nuclear medicine for advanced prostate cancer in practice].

Sophie Carina Siegmund, Philipp M Kazmierczak, Adrien Holzgreve, Christian G Stief, Jozefina Casuscelli, Marcus Unterrainer, Lena M Unterrainer

Abstract readEnglish Abstract
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In one paragraph

Article in Radiologie (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sophie Carina SiegmundKlinik und Poliklinik für Nuklearmedizin, LMU-Klinikum, LMU München, Marchioninistr. 15, 81377, München, Deutschland. Sophie.Siegmund@med.uni-muenchen.de.
Philipp M KazmierczakKlinik und Poliklinik für Radiologie, LMU-Klinikum, LMU München, München, Deutschland.
Adrien HolzgreveKlinik und Poliklinik für Nuklearmedizin, LMU-Klinikum, LMU München, Marchioninistr. 15, 81377, München, Deutschland.
Christian G StiefUrologische Klinik und Poliklinik, LMU-Klinikum, LMU München, München, Deutschland.
Jozefina CasuscelliUrologische Klinik und Poliklinik, LMU-Klinikum, LMU München, München, Deutschland.
Marcus UnterrainerKlinik und Poliklinik für Nuklearmedizin, LMU-Klinikum, LMU München, Marchioninistr. 15, 81377, München, Deutschland.
Lena M UnterrainerKlinik und Poliklinik für Nuklearmedizin, LMU-Klinikum, LMU München, Marchioninistr. 15, 81377, München, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Over the last few years diagnostic and therapeutic advances have contributed to the significant relevance of prostate-specific membrane antigen (PSMA) positron emission tomography/computed tomography (PET/CT) and PSMA radioligand therapy in patients with advanced prostate cancer (PCa). The PSMA-PET/CT has a higher accuracy for the detection of PCa metastases than the combination of CT and bone scintigraphy. Based on the theranostic approach, PSMA radioligand therapy can be performed in the castration-resistant stage in patients with sufficient PSMA expression of the tumor lesions in PSMA PET/CT and progression of PCa after chemotherapy and therapy with abiraterone or an androgen receptor signalling pathway inhibitor. Over the next few years, a large number of studies on the effectiveness of PSMA radioligand therapy in earlier stages of PCa and as part of combination therapies with other drugs will be conducted.

Indexed as

Nuclear MedicinePositron Emission Tomography Computed TomographyProstatic NeoplasmsAndrostenesGlutamate Carboxypeptidase IIHumansMaleRadiopharmaceuticalsAndrostenesGlutamate Carboxypeptidase IIRadiopharmaceuticalsmCRPCMetastasesProstatic neoplasmsPSMA-PET/CTPSMA radioligand therapy

Identifiers

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.