Evidence map›Paper›PMID 41116692›Full record

ArticleThe Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology2026

The role of sestrin2 in skeletal muscle regeneration after injury.

Chae Young Hwang, Sang-Min Park, Hoyeon Lee, Seung-Min Lee, Jeong Yi Choi, Su-Jin Baek, Taeyoung Kim, Yong Ryoul Yang, Ki-Sun Kwon

Abstract read
In one paragraph

Article in The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chae Young HwangAventi Inc., Daejeon 34141, Korea.
Sang-Min ParkCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Hoyeon LeeCollege of Pharmacy, Chungnam National University, Daejeon 34134, Korea.
Seung-Min LeeAging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Jeong Yi ChoiAging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Su-Jin BaekKorean Medicine (KM) Data Division, Korea Institute of Oriental Medicine, Daejeon 34054, Korea.
Taeyoung KimAventi Inc., Daejeon 34141, Korea.
Yong Ryoul YangAging Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology, Daejeon 34141, Korea.
Ki-Sun KwonAventi Inc., Daejeon 34141, Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite advances in the understanding of muscle degeneration, the mechanisms governing muscle regeneration under stress conditions remain poorly defined. Sestrin2 (Sesn2) is a stress-inducible gene that plays a crucial role in metabolic balance, nutrient sensing, and redox homeostasis, while protecting against muscle atrophy through multiple pathways. However, its precise role in skeletal muscle differentiation and regeneration, particularly under injury conditions, remains incompletely understood. In this study, we investigated the role of Sesn2 in skeletal muscle homeostasis and regeneration using

Indexed as

MyogenesisOxidative stressRegenerationSestrinsSkeletal muscle

Identifiers

PMID41116692
PMCPMC12723418

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.