Evidence map›Paper›PMID 41116865›Full record

ReviewCurrent treatment options in cardiovascular medicine2025

Evolving Decongestion Strategies in the Management of Acute Heart Failure.

Jeffrey George, W H Wilson Tang

Abstract readReview
In one paragraph

Review in Current treatment options in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeffrey GeorgeCase Western Reserve University, Cleveland, OH USA.
W H Wilson TangDepartment of Cardiovascular and Metabolic Sciences, Cleveland Clinic Research, Cleveland, OH USA.

Funding

International Consortium for Multimodality Phenotyping in Adults with Non-compactionR01HL146754 · NHLBI · STANFORD UNIVERSITY · PI NIEMAN, KOEN, TANG, WAI HONG WILSON · 2020 to 2023
$3.0M
NHLBI NIH HHS R01 HL146754
6 · The paper itself

Abstract

Purpose of Review: To provide an overview of the latest evidence-based treatment strategies for acute heart failure (HF), with a significant focus on recent clinical trials and their associated implications within clinical practice. Recent Findings: Recent studies have highlighted the effectiveness of urine sodium-guided decongestion, segmental nephron blockade, disease-modifying therapies, and the use of maintenance diuretics. These approaches have demonstrated significant improvements in patient outcomes, including better decongestion, reduced hospital admissions, and improved survival rates. Summary: The findings suggest a multifaceted, evidence-based approach is necessary for the effective management of acute HF. Implementing urine sodium-guided decongestion and segmental nephron blockade can enhance diuretic efficiency while disease-modifying therapies improve long-term outcomes. Maintenance diuretics play a crucial role in preventing recurrent hospitalizations.

Indexed as

Acute heart failureDiureticsGuideline-directed medical therapy

Identifiers

PMID41116865
PMCPMC12535541

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.