Evidence map›Paper›PMID 41117713›Full record

ArticleVeterinary medicine and science2025

Investigation of the Relationship Between Brain-Derived Neurotrophic Factor and Some Biochemical Parameters in Dairy Cows During the Transition Period.

Mustafa İssi, Cennet Nur Ünal, Sümeyye Babacan, Meltem Cankara

Abstract read
In one paragraph

Article in Veterinary medicine and science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Mustafa İssiDepartment of Internal Medicine, Faculty of Veterinary Medicine, Fırat University, Elazığ, Türkiye.
Cennet Nur ÜnalDepartment of Internal Medicine, Faculty of Veterinary Medicine, Bingöl University, Bingöl, Türkiye.ORCID https://orcid.org/0000-0002-8676-6490
Sümeyye BabacanDepartment of Internal Medicine, Faculty of Veterinary Medicine, Fırat University, Elazığ, Türkiye.ORCID https://orcid.org/0000-0001-8007-8315
Meltem CankaraFree Researcher, Elazığ, Türkiye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The transition period covers a period of ±21 days based on the calving day. This period is characterised by marked changes in the endocrine status of the animal, increased nutrient demand of the developing foetus and decreased feed intake. In this study, it was aimed to evaluate brain-derived neurotrophic factor (BDNF) concentrations in dairy cattle during the transition period in the prenatal and postpartum periods and to evaluate the relationship with biochemical parameters. Blood was collected from healthy cows at 254 ± 3 days prepartum and 21 ± 3 days postpartum. Metabolic profile tests aspartatamino transferase (AST), alaninamino transferase (ALT), gamma-glutamine transferase (GGT), total protein, cholesterol, urea, creatinine, calcium and phosphorus (P) parameters-were measured calorimetrically in biochemical analyser.   Beta hydroxy butyric acid (BHBA) and glucose were measured with a handheld device. Serum BDNF was analysed with a bovine-specific ELISA kit. In conclusion, serum BDNF measurement showed a similar increase among metabolic profile parameters, but no statistical correlation was detected, and it was concluded that it would be useful to evaluate negative energy balance in a larger population and with daily measurements.

Indexed as

Brain-Derived Neurotrophic FactorAnimalsCattleFemalePostpartum PeriodPregnancyBrain-Derived Neurotrophic FactorBDNFdairy cattletransition periods

Identifiers

PMID41117713
PMCPMC12539280

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.