Evidence map›Paper›PMID 41118054›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2026

Costs of productivity loss up to two years after ischaemic stroke.

Ilse Huijberts, Robert J van Oostenbrugge, Wim H van Zwam, Alida A Postma, Florentina M E Pinckaers

Abstract readMulticenter Study
In one paragraph

Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ilse HuijbertsDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands. ilse.huijberts@mumc.nl.ORCID http://orcid.org/0000-0002-4138-9855
Robert J van OostenbruggeDepartment of Neurology, Maastricht University Medical Centre+, Maastricht, The Netherlands.ORCID http://orcid.org/0000-0003-1032-9099
Wim H van ZwamDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.ORCID http://orcid.org/0000-0003-1631-7056
Alida A PostmaDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.ORCID http://orcid.org/0000-0002-1116-054X
Florentina M E PinckaersDepartment of Radiology and Nuclear Medicine, Maastricht University Medical Centre+, P. Debyelaan 25, Maastricht, 6229 HX, The Netherlands.ORCID http://orcid.org/0000-0002-8336-6897

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn the working population, diminished productivity increases the economic burden of ischaemic stroke. This study aimed to estimate costs of paid productivity losses per modified Rankin Scale (mRS) score at different time points up to two-years post-stroke. PATIENTS AND

methodsData from a multicentre cross-sectional study on post-stroke costs were utilised. Only patients with a pre-stroke professional activity were included in this study. Patients participated in a telephone mRS-interview and returned a questionnaire on paid productivity loss due to absenteeism and presenteeism in the preceding three months. Records were categorised into three-month, one-year, and two-year post-stroke time points based on the interview date. Costs of paid productivity loss were calculated using the human-capital approach (HCA) and friction cost method (FCM). Bootstrapping was combined with multiple imputation to derive mean costs per time point and mRS score (0, 1, 2, and 3-5).  

resultsOut of 1106 records, 280 respondents had a pre-stroke professional activity. Costs of paid productivity loss according to both the HCA and FCM ranged from €8980 (mRS 1) to €17,620 (mRS 3-5) in the first three months post-stroke. At one- and two years post-stroke, cost estimates according to the HCA were very similar to those at three months, while costs according to the FCM were significantly lower (0-775 euro at one year and 113-1884 euro at two years post-stroke). DISCUSSION: Costs of productivity loss following ischaemic stroke in the working population are substantial and rise with higher mRS scores.

conclusionThese estimates may be used to inform health economic evaluations.

Indexed as

Cost of IllnessEfficiencyIschemic StrokeAbsenteeismAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPresenteeismSurveys and QuestionnairesTime FactorsCosts and cost analysisHealth economicsIschemic strokeModified rankin scaleProductivity

Identifiers

PMID41118054
PMCPMC13190521

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.