Evidence map›Paper›PMID 41120472›Full record

Trial reportScientific reports2025

Relationship between dementia diagnostic characteristics and severity of depressive symptoms in a cross-sectional analysis of HOMESIDE baseline data.

Anna A Bukowska, Edyta Janus, Vanessa Pac Soo, Agnieszka Smrokowska-Reichmann, Ming Hung Hsu, Karette A Stensæth, Helen Odell-Miller, Jeanette Tamplin, Thomas Wosch, Tanara Vieira Sousa and 3 more

Registry-linked trialAbstract readMulticenter StudyRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03907748 (HOMESIDE), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03907748 nacompletednot on this map

HOMESIDE: Home-based Family Caregiver-delivered Music and Reading Interventions for People Living With Dementia: A Randomised Controlled Trial

TypeinterventionalSponsorAnglia Ruskin UniversityRan2019 to 2022Enrolled864ConditionsDementia, Dementia, Vascular, Dementia With Lewy Bodies, Dementia, MixedArmsMusic Intervention, Reading Intervention
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna A BukowskaThe University of Physical Culture in Kraków, The Institute of Applied Sciences, Motor Rehabilitation Faculty, Av. Jana Pawla II 78, 31-543, Kraków, Poland. anna.bukowska@awf.krakow.pl.ORCID http://orcid.org/0000-0003-1840-3070
Edyta JanusDepartment of Occupational Therapy, The Józef Piłsudski University of Physical Education in Warsaw, Marymoncka St. 34, 00-968, Warszawa, Poland.
Vanessa Pac SooCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.
Agnieszka Smrokowska-ReichmannThe University of Physical Culture in Kraków, The Institute of Applied Sciences, Motor Rehabilitation Faculty, Av. Jana Pawla II 78, 31-543, Kraków, Poland.
Ming Hung HsuCambridge Institute for Music Therapy Research (CIMTR), Faculty of Arts, Humanities, Education and Social Sciences, Anglia Ruskin University (ARU), East Road, Cambridge, CB1 1PT, UK.
Karette A StensæthNorwegian Academy of Music, Centre for Research in Music and Health, Slemdalsveien 11, 0369, Oslo, Norway.
Helen Odell-MillerCambridge Institute for Music Therapy Research (CIMTR), Faculty of Arts, Humanities, Education and Social Sciences, Anglia Ruskin University (ARU), East Road, Cambridge, CB1 1PT, UK.
Jeanette TamplinFaculty of Fine Arts and Music, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.
Thomas WoschFaculty of Applied Social Sciences, Technical University of Applied Sciences Würzburg-Schweinfurt, Munzstrasse 12, 97070, Wurzburg, Germany.
Tanara Vieira SousaFaculty of Fine Arts and Music, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.
Karen E LambCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.
Sabine BraatCentre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.
Felicity A BakerFaculty of Fine Arts and Music, The University of Melbourne, Grattan Street, Parkville, Melbourne, VIC, 3010, Australia.

Funding

Alzheimer's Society, UK grant no. 462Federal Ministry of Education and Research Germany 01ED1901National Health and Medical Research Council, Australia GNT1169867Norwegian Research Council Project number 298995The National Centre for Research and Development, Poland JPND/04/2019
6 · The paper itself

Abstract

Depression is a common comorbidity in dementia, with prevalence ranging from 20 to 60% across different countries. This study examined whether depressive symptom severity levels differ by dementia characteristics and country of residence in people living with dementia. This cross-sectional analysis used baseline data from 376 participants in the HOMESIDE trial. Linear regression models examined differences in depressive symptom severity levels by dementia stage, type, severity, and country. In this sample (57% male, mean age 76.6 years), depressive symptom scores were higher for people with severe cognitive impairment than those with mild dementia (MMSE 24-30) (adjusted mean difference: 3.78, 95% CI 1.60-5.96). Mean depressive symptom severity was lower in Norway, Germany, and United Kingdom compared to Australia, with no significant difference for Poland. No apparent differences by dementia type or stage were found. Depressive symptom severity levels differed by cognitive impairment severity and country. Cross-national differences likely reflect a complex interplay of healthcare systems, cultural factors, family support structures, and societal approaches to dementia care. Regular depressive symptom screening is recommended, particularly for severe dementia.Trial registration: ACTRN12618001799246 (Australian New Zealand Clinical Trials Registry) and NCT03907748 (ClinicalTrials.gov).

Indexed as

DementiaDepressionAgedAged, 80 and overAustraliaCognitive DysfunctionCross-Sectional StudiesFemaleGermanyHumansMalePrevalenceSeverity of Illness IndexUnited KingdomCognitive impairmentCross-national comparisonDementiaDepressionHOMESIDE

Identifiers

PMID41120472
PMCPMC12541064

What Socratic holds

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LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.