Evidence map›Paper›PMID 41120779›Full record

ArticleJournal of molecular neuroscience : MN2025

The Causal Relationship Between Palmitoylation Genes and Parkinson's Disease: A Mendelian Randomization Study.

Jin Qiu, Jiali Yang, Ruisen Zhu, DeHai Xian, Kaiwen Yang

Abstract read
PubMed Publisher
In one paragraph

Article in Journal of molecular neuroscience : MN, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jin Qiu *School of Basic Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou City, Sichuan Province, China.
Jiali Yang *School of Basic Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou City, Sichuan Province, China.
Ruisen ZhuSchool of Basic Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou City, Sichuan Province, China.
DeHai XianSchool of Basic Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou City, Sichuan Province, China. 13340781717@163.com.
Kaiwen YangSchool of Basic Medical Sciences, Southwest Medical University, No. 1, Section 1, Xianglin Road, Luzhou City, Sichuan Province, China. 18982760833@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This work examined the causal link between palmitoylation-related genes and Parkinson's disease (PD) by Mendelian randomization (MR). We conducted two-sample Mendelian randomization utilizing genome-wide association study (GWAS) summary statistics. Expression quantitative trait loci (eQTL) data for palmitoylation genes were sourced from eQTLGen, whilst PD data were derived from the GWAS Catalogue (15,056 cases, 12,637 controls) and FinnGen (4,681 cases, 407,500 controls). Instrumental variables (p < 5 × 10⁻⁶, r

Indexed as

AcyltransferasesLipoylationParkinson DiseaseGenome-Wide Association StudyHumansMendelian Randomization AnalysisPolymorphism, Single NucleotideQuantitative Trait LociAcyltransferasesGenome-wide association studyMendelian randomizationPalmitoylationParkinson’s diseaseZDHHC8

Identifiers

PMID41120779

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.