Evidence map›Paper›PMID 41120987›Full record

ArticleBMC public health2025

Association between long-term exposure to air pollutant mixture and the risk of Alzheimer's disease among older people: a prospective cohort study in China.

Hao Fu, Tao Zhang, Xue Gu, Fudong Li, Mingjuan Jin, Fan He, Fangrong Fei

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hao FuDepartment of Epidemiology and Biostatistics at School of Public Health, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Tao ZhangZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
Xue GuZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
Fudong LiZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
Mingjuan JinDepartment of Epidemiology and Biostatistics at School of Public Health, Zhejiang University School of Medicine, Hangzhou, 310058, China.
Fan HeZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China.
Fangrong FeiZhejiang Provincial Center for Disease Control and Prevention, 3399 Binsheng Road, Hangzhou, 310051, China. frfei@cdc.zj.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlzheimer's disease (AD) has garnered significant attention in recent years. However, evidence of the association between air pollutant mixture and AD from prospective studies has not been systematically explored. We aimed to examine the associations of combined exposure to nitrogen dioxide (NO

methodsOur study was based on the Zhejiang Province Major Public Health Surveillance (ZJMPHS) Program. The concentrations of five air pollutants were estimated via the empirical Bayesian kriging (EBK) spatial interpolation method, and we applied a weighted joint air pollution score (JAPS) to evaluate their combined effects. AD was ascertained according to the Diagnostic and Statistical Manual of Mental Disorders and Statistics (DSM-IV) and Communicative Disorders and Stroke and the Alzheimer's Disease and Related Disorders Association-Alzheimer's Criteria (NINCDS-ADRDA). The Cox proportional hazards models were used to explore the associations between air pollution and AD.

resultsA total of 10,055 participants aged ≥ 60 years were included in the analysis. During a follow-up period of 34,764 person-years, 879 AD cases were identified. SO

conclusionsThis study suggested that high concentration of air pollutant mixture could increase the risk of AD. Moreover, it is important to weigh the impact of exercise under extremely high air pollution and pay attention to those who live alone.

Indexed as

Air PollutantsAir PollutionAlzheimer DiseaseEnvironmental ExposureAgedAged, 80 and overChinaFemaleHumansMaleMiddle AgedNitrogen DioxideOzoneParticulate MatterProspective StudiesRisk FactorsAir PollutantsNitrogen DioxideOzoneParticulate MatterSulfur DioxideAir pollutionAlzheimer’s diseaseCohort studyCombined effect

Identifiers

PMID41120987
PMCPMC12541937

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.