ReviewHepatology forum2025
Role of essential oils in preventing hepatotoxicity: A comprehensive review.
Review in Hepatology forum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Targeted phytotherapy: essential oils, multi-target cancer action & nanodelivery.Frontiers in oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hepatotoxicity represents one of the significant and challenging health concerns at the worldwide level. To overcome this condition, essential oil can act as a natural therapeutic in alleviating hepatic disorders caused by toxins, drugs, alcohol, or infections. Various aromatic plants such as Citrus species, Allium species, spices, and rosemary species contain bioactive compounds-mainly terpenes, phenolics, flavonoids, and sulfur-containing compounds. These bioactive compounds possess excellent antioxidant potential to neutralize free radicals and promote the endogenous antioxidant defense system, such as SOD, catalase, Gpx, and others as well. In addition to this, they exhibit anti-inflammatory potential to regulate inflammatory cascades and cytokine levels, while their detoxification mechanism stimulates the liver's capacity to eradicate harmful substances. Although previous research has documented that essential oil exhibits the ability to protect the liver from chronic diseases-mainly fibrosis, non-alcoholic fatty liver disease (NAFLD), and drug-induced hepatotoxicity-by modulating lipid metabolism, hepatocyte integrity, the antioxidant defense system, and pathological factors, future research is still required to evaluate its efficacy, bioavailability, safe doses, and explore synergistic formulations. Keeping these perspectives in mind, the current review is planned to highlight the hepatoprotective properties of essential oils, their underlying mechanisms, and their prospective contribution to the development of natural therapeutics for liver health.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.