ReviewFrontiers in nutrition2025
Offspring's exposome: a narrative review on the influence of early-life factors on childhood obesity risk.
Review in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Screen Time, Unhealthy Eating Behaviors, and Associated Health Risks in Children: A Narrative Review.Children (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood obesity has emerged as a global health challenge, with significant long-term health consequences, including an increased risk of non-communicable diseases. The "first 1,000 days" period of life is a critical window for shaping long-term health outcomes. This narrative review aims to explore the role of environmental exposures, categorized within the exposome framework, in developing childhood obesity. The exposome encompasses three domains: general external exposures (e.g., air pollution, urbanization), specific external exposures [e.g., nutrition, physical activity, socioeconomic status (SES)], and internal exposures (e.g., metabolic responses, oxidative stress). Evidence identifies risk factors such as maternal smoking during pregnancy, early-life exposure to endocrine-disrupting chemicals, and air pollution, which contribute to obesogenic processes. In contrast, protective factors include access to green and blue spaces, exclusive breastfeeding, adequate complementary feeding, regular physical activity, limited screen time, and sufficient sleep, which support healthy growth trajectories. Findings regarding SES, perfluoroalkyl and polyfluoroalkyl substances exposure, and human breast milk macronutrient composition remain heterogeneous and context-dependent. The findings highlight the need to integrate public health strategies addressing modifiable environmental and lifestyle factors. Identifying a "healthy exposome" that protects against obesity risk can steer the development of personalized prevention strategies, ultimately reducing the burden of obesity and associated diseases.
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What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.