ArticleBMC urology2025
Oxidative balance scores and overactive bladder: mediating effects of oxidative stress and inflammatory factors.
Article in BMC urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Multimodal Biomarker and Ultrasound Profiling in Women with Overactive Bladder: A Prospective Case-Control Study.International urogynecology journal · 2026Article
- Review
- Dietary habits and adherence to the Mediterranean diet in a cohort of Parkinson's disease patients in Lithuania.Frontiers in nutrition · 2026Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
backgroundFew studies have investigated the comprehensive impact of dietary and lifestyle factors on overactive bladder (OAB). This study aimed to explore the associations of the Oxidative Balance Score (OBS) and its components-dietary OBS (DOBS) and lifestyle OBS (LOBS)-with OAB and their underlying mechanisms.
methodsData were extracted from the 2007-2018 National Health and Nutrition Examination Survey (NHANES). Weighted multivariate logistic regression was employed to evaluate associations between OBS/DOBS/LOBS and OAB. Mediation analyses were conducted to assess the potential mediating roles of oxidative stress and inflammatory factors.
resultsThe study included 16,493 participants, including 2,950 OAB patients. Weighted multivariate analysis revealed a consistent inverse association between LOBS and OAB (OR: 0.89; 95% CI: 0.86-0.92; P < 0.001), while no stable correlations were observed for OBS or DOBS. Mediation analyses demonstrated significant mediating effects of albumin, bilirubin, white blood cells (WBC), neutrophils, monocytes, Systemic Immunity-Inflammation Index (SII), and Systemic Inflammatory Response Index (SIRI) in the LOBS-OAB association, with mediation proportions of 15.6%, 7.7%, 9.0%, 8.1%, 4.1%, 1.2%, and 3.5%, respectively.
conclusionsHigher LOBS was inversely associated with OAB risk, partially explained by oxidative stress and inflammatory factors, whereas neither OBS nor DOBS showed stable associations with OAB.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.