ArticleBMC complementary medicine and therapies2025
Phytochemical investigation, in vitro antioxidant, antibacterial activities of the leaf and fruit extracts of Hypericum revolutum Vahl (Amija), and essential oil composition of the leaf extract.
Article in BMC complementary medicine and therapies, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Antioxidant and Health-Related Effects of Tannins: From Agri-Food By-Products to Human and Animal Health.Antioxidants (Basel, Switzerland) · 2026Review
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4 authors.
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Abstract
Hypericum revolutum Vahl, a flowering plant in the Hypericaceae family, is traditionally used in Ethiopia to treat febrile illnesses in humans and combat diarrhea in livestock. It is known for its significant analgesic and anti-inflammatory activities. This study aims to investigate the phytochemical composition, antioxidant activity, and antibacterial efficacy of the leaf and fruit extracts, as well as the essential oil obtained from the leaves. Essential oil was extracted by hydrodistillation, while crude extracts were obtained through successive maceration using petroleum ether, chloroform, and methanol solvents. Gas chromatography-mass spectrometry (GC-MS) analysis identified major compounds, including 1R-alpha-Pinene (59.21%) and D-Limonene (7.979%). Phytochemical screening of methanol extracts revealed the presence of flavonoids, phenols, tannins, saponins, and alkaloids. Quantitative analysis revealed high total phenolic (162.04 ± 0.77 mg gallic acid equivalents (GAE)/g) and total flavonoid content (181.96 ± 8.35 mg of quercetin equivalents (QE)/g) in fruit and leaf extracts, respectively. Antioxidant activity, assessed by the DPPH assay, showed IC
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