Evidence mapPaperPMID 41127230Full record

ArticleSultan Qaboos University medical journal2025

Anthracycline-Induced Cardiomyopathy in Breast Cancer Patients in Oman:

Hussain A Al-Lawati, Khalid Al Baimani, Mohammed N Al Rawahi

Abstract read
In one paragraph

Article in Sultan Qaboos University medical journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Hussain A Al-LawatiIntensive Care Unit, Royal Hospital, Muscat, Oman.
Khalid Al BaimaniMedical Oncology Department, Sultan Qaboos Comprehensive Cancer Care & Research Centre, University Medical City, Muscat, Oman.
Mohammed N Al RawahiCardiology Department, Sultan Qaboos University Hospital, University Medical City, Muscat, Oman.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Anthracyclines are widely used in the treatment of breast cancer. One of the known adverse effects of anthracyclines is anthracycline-induced cardiomyopathy. Studies done worldwide showed that the prevalence of chemotherapy-induced cardiomyopathy is approximately 9%. However, studies evaluating this complication prevalence, risk factors and cumulative dose are lacking in Oman. This study aimed to investigate the prevalence of anthracycline-induced cardiomyopathy among breast cancer patients in Oman. Methods: This retrospective study included all breast cancer patients who received anthracycline-based chemotherapy exclusively between September 2008 and December 2020 at Sultan Qaboos University Hospital in Muscat. Patients with partial treatment, coexisting heart failure and who did not receive anthracycline as part of the chemotherapy regimen were excluded. Chemotherapy-induced cardiomyopathy was defined as a drop of left ventricular ejection fraction >10% from the patient's baseline during or after receiving anthracycline-based chemotherapy. Results: A total of 385 patients were included in this study of which 39 (10.1%) developed cardiomyopathy after exposure to anthracyclines. The mean cumulative dose of doxorubicin among these patients was 239 mg/m Conclusions: Anthracycline-induced cardiomyopathy was influenced by various cardiovascular risk factors as well as trastuzumab exposure. Further studies are recommended to investigate the prevention and management of anthracycline-induced cardiomyopathy.

Indexed as

AnthracyclinesBreast NeoplasmsCardiomyopathiesAdultAgedFemaleHumansMiddle AgedOmanPrevalenceRetrospective StudiesRisk FactorsAnthracyclinesAdverse EffectsAnthracyclinesBreast NeoplasmsCardiomyopathiesDoxorubicinDrug TherapyOmanToxicity

Identifiers

PMID41127230
PMCPMC12538945

What Socratic holds

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.