Evidence mapPaperPMID 41129088Full record

ArticleThe international journal of cardiovascular imaging2025

Coronary microvascular dysfunction in gestational diabetes: insights on possible mechanism from a large institutional registry.

Mustafa Caliskan, Mumtaz Takir, Ahmet Eren Caliskan, Fatma Betul Celik, Lutfullah Castur, Erhan Eken, Tolga Sinan Guvenc

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Article in The international journal of cardiovascular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mustafa CaliskanDepartment of Cardiology, Istanbul Medeniyet University Göztepe Süleyman Yalçın City Hospital, Istanbul, Turkey. caliskandr@gmail.com.
Mumtaz TakirDepartment of Endocrinology, Istanbul Medeniyet University Göztepe Süleyman Yalçın City Hospital, Istanbul, Turkey.
Ahmet Eren CaliskanBezmialem University Medical Faculty, Istanbul, Turkey.
Fatma Betul CelikDepartment of Cardiology, Istanbul Medeniyet University Göztepe Süleyman Yalçın City Hospital, Istanbul, Turkey.
Lutfullah CasturDepertment of Internal medicine, Istanbul Medeniyet University Göztepe Süleyman Yalçın City Hospital, Istanbul, Turkey.
Erhan EkenDepertment of Internal medicine, Istanbul Medeniyet University Göztepe Süleyman Yalçın City Hospital, Istanbul, Turkey.
Tolga Sinan GuvencDepartment of Cardiology, Istinye University School of Medicine, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gestational diabetes is associated with an increased risk of coronary artery disease (CAD) and adverse cardiovascular events in later life. Coronary microvascular dysfunction is a common precursor of CAD. Although microvascular dysfunction is common in gestational diabetes (GDM), the exact mechanisms remain unknown. We aimed to study the associations between coronary flow reserve (CFR) with common biomarkers of hyperglycemia, insulin resistance, inflammation and oxidative stress. Measurement of CFR was performed noninvasively using echocardiography in all patients. Patients with a low CFR (≤ 2.5) had higher HbA1c%, HOMA-IR, triglyceride-glucose index, uric acid, and total and non-HDL cholesterol as compared to those with a normal CFR (> 2.5). On univariate analysis, there was strong evidence favoring an association between CFR with HbA1c% (r=-0.32, p < 0.001, BF

Indexed as

Coronary Artery DiseaseCoronary CirculationDiabetes, GestationalMicrocirculationAdultBiomarkersBlood GlucoseCross-Sectional StudiesFemaleGlycated HemoglobinHumansInflammation MediatorsInsulin ResistanceOxidative StressPredictive Value of TestsPregnancyBiomarkersBlood GlucoseGlycated Hemoglobinhemoglobin A1c protein, humanInflammation MediatorsUric AcidCoronary artery diseaseCoronary microvascular dysfunctionDiabetes mellitusGestational diabetesInsulin resistanceMicrocirculation

Identifiers

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.