Evidence map›Paper›PMID 41129229›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2025

Nir2 crystal structures reveal a phosphatidic acid-sensing mechanism at ER-PM contact sites.

Dongyoung Kim, Seowhang Lee, Youngsoo Jun, Changwook Lee

Abstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Phosphatidylinositol transfer protein α binds microcolins in its open conformation.Acta crystallographica. Section D, Structural biology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dongyoung KimDepartment of Life Sciences, Korea University, Seoul 02841, South Korea.
Seowhang LeeDepartment of Biological Sciences, Ulsan National Institute of Science and Technology, Ulsan 44919, South Korea.
Youngsoo JunSchool of Life Sciences, Gwangju Institute of Science and Technology, Gwangju 61005, South Korea.ORCID 0000-0002-2387-032X
Changwook LeeDepartment of Life Sciences, Korea University, Seoul 02841, South Korea.ORCID 0000-0002-3016-9478

Funding

National Research Foundation of Korea (NRF) RS-2021-NR056528National Research Foundation of Korea (NRF) RS-2021-NR059330
6 · The paper itself

Abstract

Agonist-induced activation of phosphoinositide-specific phospholipase C (PLC) converts phosphatidylinositol 4,5-bisphosphate [PI(4,5)P

Indexed as

Arabidopsis ProteinsCell MembraneEndoplasmic ReticulumPhosphatidic AcidsCrystallography, X-RayHumansModels, MolecularProtein BindingProtein DomainsArabidopsis ProteinsPhosphatidic Acidscrystal structurelipid transfer proteinmembrane contact siteNir2PLC signaling

Identifiers

PMID41129229
PMCPMC12582312

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.