ArticleCommunications biology2025
Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance.
Article in Communications biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Trophic Antioxidant Transfer as a Measure for Scalable Coral Conservation Strategies.Antioxidants (Basel, Switzerland) · 2026Article
- Review
- Sterols are key to coral larvae survival, swimming capacity, and thermal tolerance.Communications biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Corals at very early life stages face high mortality bottlenecks, limiting natural stock-recruitment and the success of restoration and aquaculture strategies reliant on sexual reproduction. Nutrient availability and quality, particularly lipids, are critical for larval survival, dispersal, and settlement, yet the specific lipids influencing early-stage fitness remain unclear. Since measuring lipid depletion in non-surviving larvae is impractical, we developed a targeted supplementation approach to identify nutrients that enhance larval fitness. Supplementing Acropora spathulata larvae with nanoparticle-encapsulated triacylglycerols and sterols significantly improved swimming distance and speed, indicating enhanced dispersal potential. Supplementation with sterols, which are essential for cell structure and metamorphosis, also increased settlement rates. Furthermore, juveniles developed from larvae fed with sterols and omega-3-rich fish oils demonstrated superior performance under controlled and thermal stress conditions during the first six months, while those supplemented with Calanus oil also enhanced survival under elevated temperatures. Lipid profiling revealed key sphingolipids, glycerophospholipids, and fatty acids likely responsible for the improved fitness of fed larvae. Our approach highlights the critical role of lipid composition and availability during coral early life stages and demonstrates the potential of targeted nutritional supplementation to address nutrient deficiencies, enhance coral resilience, and support restoration and aquaculture efforts.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.