Evidence map›Paper›PMID 41131426›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

The association of complete blood count parameters and obstructive sleep apnea in the Cypriot population.

A Granitsas, K Cholidou, C Bartsokas, A Charokopos, G Stathopoulos, T Adamidi, P Steiropoulos, A Pataka, G Trakada

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

A GranitsasLaboratory and Clinical Sleep Medicine, Evangelismos Hospital - MSc in Sleep-Related Breathing Disorders, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece. angranitsas@gmail.com.
K CholidouFirst Respiratory Medicine Department, National and Kapodistrian University of Athens, Medical School, "Sotiria" Chest Diseases Hospital, Athens, Athens, Greece.
C BartsokasDepartment of General Surgery, Nicosia General Hospital, Nicosia, Cyprus.
A CharokoposDepartment of Pulmonary Medicine, Nicosia General Hospital, Nicosia, Palaios Dromos Lefkosias Lemesou 215, 2029, Nicosia, Cyprus.
G StathopoulosDepartment of Pulmonary Medicine, Nicosia General Hospital, Nicosia, Palaios Dromos Lefkosias Lemesou 215, 2029, Nicosia, Cyprus.
T AdamidiDepartment of Pulmonary Medicine, Nicosia General Hospital, Nicosia, Palaios Dromos Lefkosias Lemesou 215, 2029, Nicosia, Cyprus.
P SteiropoulosDepartment of Respiratory Medicine, University General Hospital of Alexandroupolis, Alexandroupolis, Greece.
A PatakaRespiratory Failure Unit, G Papanikolaou Hospital, Thessaloniki, Greece.
G TrakadaLaboratory and Clinical Sleep Medicine, Evangelismos Hospital - MSc in Sleep-Related Breathing Disorders, School of Medicine, National and Kapodistrian University of Athens, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe hemocyte profile is a frequently requested clinical laboratory test. However, the analysis of blood cell indexes of obstructive sleep apnea (OSA) patients in previous studies was not decisive. This study aimed to fully analyze the blood count patterns in OSA patients.

methodsWe retrospectively studied 114 patients, referred to the sleep center of Nicosia General Hospital in Cyprus and had sleep studies performed from July 2022 until October 2024. Based on apnea hypopnea index (AHI), patients were divided into four groups: control (AHI < 5, n = 12), mild OSA (5 ≦ AHI < 15, n = 35), moderate OSA (15 ≦ AHI < 30, n = 28), and severe OSA (AHI ≧ 30, n = 39). We evaluated sleep parameters by type III with Nox T3s home sleep testing device. Patients with central sleep apnea syndrome, chronic respiratory failure and known haematological diseases were excluded.

resultsSignificant positive linear correlations of hematocrit, hemoglobin and red blood cells (RBC) with oxygen desaturation index (ODI) were observed, and inverse linear correlations with minimum SpO2. There was a significant positive linear correlation between hematocrit and duration SpO2 < 90%, but not with average SpO2. The values of mean platelet volume (MPV) had statistically significant positive linear correlations with ODI and minimum SpO2.

conclusionsOur results indicate that subjects with severe OSA had higher hematocrit levels than subjects with no OSA or mild to moderate OSA. Even though MPV is associated with a higher degree of nocturnal hypoxemia, among the laboratory parameters that were investigated, only hematocrit can be used as an inexpensive tool for triaging OSA patients for evaluation in sleep laboratories.

Indexed as

Sleep Apnea, ObstructiveAdultAgedBlood Cell CountCyprusFemaleHumansMaleMiddle AgedPolysomnographyRetrospective StudiesCardiovascular diseaseHematocritMean platelet volumeObstructive sleep apneaRed cell distribution width

Identifiers

PMID41131426

What Socratic holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.