ArticleJournal of translational medicine2025
Muscle quality decline and fat infiltration in non-elderly OSA patients: associations with metabolic abnormalities.
Article in Journal of translational medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
2 citing papers in PubMed.
- Benchmarking inflammation-nutrition and TyG-related indices for 5-year mortality risk in adults with questionnaire-defined obstructive sleep apnea: a survey-weighted NHANES derivation cohort with multicenter external validation.Journal of translational medicine · 2026Article
- Age-related adiponectin resistance in human skeletal muscle dysfunction: in vivo and in vitro evidence.Journal of translational medicine · 2026Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundObstructive sleep apnea (OSA) and adverse muscle alterations are significant age-related disorders associated with cardiovascular and metabolic morbidities. However, their relationship in non-elderly populations remains unclear.
methodsThis study enrolled 52 hypertensive patients aged below 60 years (mean age: 48.5 ± 7.6 years), divided into OSA (n = 29, apnea-hypopnea index [AHI] ≥ 5) and control (n = 23) groups. Muscle quantity (erector spinae muscle [ESM] cross-sectional area [CSA], normalized CSA indices: CSA/height
resultsThe OSA group had higher BMI (27.3 ± 4.3 vs 24.8 ± 3.2 kg/m
conclusionOSA is associated with reduced muscle quality and increased fat infiltration in non-elderly hypertensive patients, and linked to metabolic abnormalities.
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Registered trials
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