Evidence map›Paper›PMID 41131762›Full record

ArticleBeijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences2025

[Expression of lumican protein in serum of patients with rheumatoid arthritis and its correlation with disease and immune activities].

Ju Yang, Jing Xu, Juhua Dai, Lianjie Shi

Abstract readEnglish Abstract
PubMed Full text at PMC
In one paragraph

Article in Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ju YangDepartment of Geriatrics, Suining Central Hospital, Suining 629000, Sichuan, China.
Jing XuDepartment of Rheumatology and Immunology, Peking University International Hospital, Beijing 102206, China.
Juhua DaiDepartment of Clinical Laboratory, Peking University International Hospital, Beijing 102206, China.
Lianjie ShiDepartment of Rheumatology and Immunology, Peking University Shougang Hospital, Beijing 100144, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the serum level of lumican (LUM) and its clinical correlation with disease and immune activities in patients with rheumatoid arthritis (RA).

methodsThe serum LUM levels in both RA patients and health controls (HCs) were detected by enzyme-linked immunosorbent assay (ELISA). The clinical and laboratory data of the patients were collected. The LUM levels in the patients with different clinical features were analyzed. The correlation between the clinical data, laboratory parameters, and serum LUM levels were also analyzed. Independent samples

resultsThe levels of LUM were elevated in the RA patients than in the HCs (

conclusionLUM, a cyclocitrullinated protein, might be a promising biomarker which could reflect both disease activity and immune activity in RA.

Indexed as

Arthritis, RheumatoidChondroitin Sulfate ProteoglycansKeratan SulfateAdultAgedBlood SedimentationC-Reactive ProteinEnzyme-Linked Immunosorbent AssayFemaleHumansLumicanMaleMiddle AgedRheumatoid FactorChondroitin Sulfate ProteoglycansC-Reactive ProteinKeratan SulfateLumicanLUM protein, humanRheumatoid FactorAnti-citrullinated protein antibodiesLumicanRheumatoid arthritisRheumatoid factor

Identifiers

PMID41131762
PMCPMC12549364

What Socratic holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.